辐射诱导肺损伤的生物学
Biology of Radiation-Induced Lung Injury.
机构信息
Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD.
Radiation Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD.
出版信息
Semin Radiat Oncol. 2021 Apr;31(2):155-161. doi: 10.1016/j.semradonc.2020.11.006.
Abstract
Radiation-induced lung injury encompasses radiation-induced pneumonitis, inflammation of the lung which may manifest as a dose-limiting acute or subacute toxicity, and radiation-induced lung fibrosis, a late effect of lung exposure to radiation. This review aims to highlight developments in molecular radiation biology of radiation-induced lung injury and their implications in clinical practice.
摘要
放射性肺损伤包括放射性肺炎，这是一种肺部炎症，可能表现为剂量限制的急性或亚急性毒性，以及放射性肺纤维化，这是肺部暴露于辐射后的一种晚期效应。本综述旨在强调放射性肺损伤的分子放射生物学方面的进展及其在临床实践中的意义。
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