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菊粉对钙代谢和骨骼健康的影响。

Effects of inulin on calcium metabolism and bone health.

机构信息

Department of Nutrition and Dietetics, Faculty of Health Sciences, Istanbul Medipol University, Istanbul, Turkey.

Department of Nutrition and Dietetics, Faculty of Health Sciences, Sanko University, Gaziantep, Turkey.

出版信息

Int J Vitam Nutr Res. 2023 Feb;93(1):85-96. doi: 10.1024/0300-9831/a000700. Epub 2021 Feb 22.

DOI:10.1024/0300-9831/a000700
PMID:33611985
Abstract

Inulin, a dietary fibre found in the roots of many plants, has positive effects on health. It is particularly noteworthy due to its positive impact on calcium metabolism. Inulin has significant functions, such as improving calcium absorption through passive diffusion, bolstering calcium absorption via ion exchange and expanding the absorption surface of the colon by stimulating cell growth. In addition, inulin boosts calcium absorption by increasing calcium solubility, stimulating levels of calcium-binding protein expression and increasing useful microorganisms. It increases calbindin levels and stimulates transcellular active calcium transport. An inulin intake of least 8-10 g/day supports calcium absorption and total body bone mineral content/density in adolescents through its known mechanisms of action. It also significantly enhances calcium absorption and improves bone health in postmenopausal women and adult men. Sustained and sufficient inulin supplementation in adults has a positive effect on calcium metabolism and bone mineral density.

摘要

菊粉是一种存在于多种植物根茎中的膳食纤维,对健康有积极影响。它特别值得注意,因为它对钙代谢有积极影响。菊粉具有多种功能,如通过被动扩散促进钙吸收,通过离子交换增强钙吸收,通过刺激细胞生长扩大结肠吸收表面。此外,菊粉通过增加钙溶解度、刺激钙结合蛋白表达水平以及增加有益微生物来促进钙吸收。它增加钙结合蛋白的水平并刺激细胞间主动钙转运。通过其已知的作用机制,每天至少摄入 8-10 克菊粉可支持青少年的钙吸收和全身骨矿物质含量/密度。它还显著提高了绝经后妇女和成年男性的钙吸收和骨骼健康。成年人持续和充足的菊粉补充对钙代谢和骨矿物质密度有积极影响。

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