Department of Parasitology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Department of Medicine, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.
Trop Biomed. 2020 Sep 1;37(3):599-608. doi: 10.47665/tb.37.3.599.
This cross-sectional study involving 86 adult asthmatic patients aimed to determine the relationship between Toxocara seropositivity and severity of asthma in adult asthmatics and investigate the risk factors for Toxocara infection. In all cases, T. canis IgG level was measured using an anti-Toxocara IgG enzyme-linked immunosorbent assay kit. Total serum IgE and eosinophil count were also determined. The anti-Toxocara IgG seropositivity was 68.6% among asthmatic patients. There were no statistically significant associations between Toxocara seroprevalence and other risk factors, clinical symptoms of asthma and high level of total serum IgE and eosinophilia. Pet ownership could be an important risk factor for Toxocariasis. Having a pet at home and wheezing were significantly associated with Toxocara seropositivity in adult asthmatic patients.
本横断面研究纳入了 86 例成年哮喘患者，旨在确定 Toxocara 血清阳性与成年哮喘患者哮喘严重程度之间的关系，并探讨 Toxocara 感染的危险因素。在所有情况下，均使用抗 Toxocara IgG 酶联免疫吸附测定试剂盒测量 T. canis IgG 水平。还测定了总血清 IgE 和嗜酸性粒细胞计数。哮喘患者的抗 Toxocara IgG 血清阳性率为 68.6%。Toxocara 血清流行率与其他危险因素、哮喘的临床症状以及总血清 IgE 和嗜酸性粒细胞增多之间无统计学显著关联。宠物拥有可能是旋毛虫病的一个重要危险因素。家中养宠物和喘息与成年哮喘患者的 Toxocara 血清阳性显著相关。
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