Kustimur Semra, Dogruman Al Funda, Oguzulgen Kivilcim, Bakir Hatice, Maral Isil, Turktas Haluk, Tuzun Hakan
Department of Medical Microbiology, Gazi University Medical Faculty, 06500 Besevler, Ankara, Turkey.
Trans R Soc Trop Med Hyg. 2007 Mar;101(3):270-4. doi: 10.1016/j.trstmh.2006.08.013. Epub 2006 Nov 13.
The aim of this study was to determine the seroprevalence of toxocariasis in adult asthmatics and to assess its relationship with risk factors. A total of 124 asthmatic and 60 control group subjects were included in the study. Of the asthmatic patients, 61 (49.2%) were atopic and 63 non-atopic (50.8%). The anti-Toxocara IgG (Toxocara IgG CELISA Cellabs, Australia) positivity rate for all asthmatic cases was 9.7%. There was no significant difference between the asthmatic cases and the control group regarding anti-Toxocara IgG positivity (P>0.05). When risk factors were analyzed, there was a statistically significant difference between the control group subjects and patients with non-atopic asthma and also between the atopic asthmatic patients and the patients with non-atopic asthma regarding pets being under veterinary control (P<0.05). The percentages of those who had their pets defecate indoors were 0, 15 and 8.6%, respectively, for the control subjects, patients with non-atopic asthma and those with atopic asthma. There was a statistically significant difference when the control group subjects were compared to the patients with atopic asthma (P<0.05).
本研究的目的是确定成年哮喘患者中弓蛔虫病的血清流行率，并评估其与危险因素的关系。该研究共纳入了124名哮喘患者和60名对照组受试者。在哮喘患者中，61名（49.2%）为特应性患者，63名（50.8%）为非特应性患者。所有哮喘病例的抗弓蛔虫IgG（澳大利亚Cellabs公司的弓蛔虫IgG CELISA检测法）阳性率为9.7%。哮喘病例与对照组在抗弓蛔虫IgG阳性方面无显著差异（P>0.05）。在分析危险因素时，对照组受试者与非特应性哮喘患者之间以及特应性哮喘患者与非特应性哮喘患者之间在宠物接受兽医管理方面存在统计学显著差异（P<0.05）。对照组受试者、非特应性哮喘患者和特应性哮喘患者中，宠物在室内排便的比例分别为0%、15%和8.6%。对照组受试者与特应性哮喘患者相比存在统计学显著差异（P<0.05）。
