一名患有色素性结膜病变患者的结膜上皮内瘤变
Conjunctival Intraepithelial Neoplasia in a Patient Presenting with Pigmented Conjunctival Lesion.
作者信息
Chaidaroon Winai, Dejkriengkraikul Chutikarn, Isipradit Sirawit, Lertprasertsuke Nirush
机构信息
Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
Department of Pathology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
出版信息
Case Rep Ophthalmol. 2021 Jan 21;12(1):77-82. doi: 10.1159/000510570. eCollection 2021 Jan-Apr.
We report a case of conjunctival intraepithelial neoplasia (CIN) in a patient presenting with the pigmented conjunctival lesion. This study involved a 56-year-old woman that presented with right eye irritation for 1 month. She noticed brownish pigmentation arising from her right nasal conjunctiva and growing slowly over time. Biomicroscopic examination showed a gelatinous pigmented conjunctival mass with feeder vessels. Conjunctival impression cytology (CIC) was done and reported as CIN. Treatment was started with 0.02% mitomycin-C eye drops. The conjunctival lesion responded well to medication. This report shows that CIN can manifest as a pigmented tumor, resembling melanoma. CIC plays a role in the diagnosis of this condition. This tumor responded well with 0.02% mitomycin-C eye drops.
我们报告了一例患有色素性结膜病变的结膜上皮内瘤（CIN）患者。本研究涉及一名56岁女性，她右眼不适1个月。她注意到右鼻侧结膜出现褐色色素沉着，且随时间缓慢生长。生物显微镜检查显示为带有滋养血管的胶状色素性结膜肿物。进行了结膜印片细胞学检查（CIC），报告结果为CIN。开始用0.02%丝裂霉素-C滴眼液进行治疗。结膜病变对药物治疗反应良好。本报告表明，CIN可表现为色素性肿瘤，类似黑色素瘤。CIC在这种疾病的诊断中发挥作用。该肿瘤对0.02%丝裂霉素-C滴眼液反应良好。
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