压力之下：细菌利用相容性溶质生物合成和摄取系统对高盐度的响应及启示

Gregory Gwendolyn J, Boyd E Fidelma

Department of Biological Sciences, University of Delaware, Newark, DE 19716, United States.

Comput Struct Biotechnol J. 2021 Feb 1;19:1014-1027. doi: 10.1016/j.csbj.2021.01.030. eCollection 2021.

Bacteria have evolved mechanisms that allow them to adapt to changes in osmolarity and some species have adapted to live optimally in high salinity environments such as in the marine ecosystem. Most bacteria that live in high salinity do so by the biosynthesis and/or uptake of compatible solutes, small organic molecules that maintain the turgor pressure of the cell. Osmotic stress response mechanisms and their regulation among marine heterotrophic bacteria are poorly understood. In this review, we discuss what is known about compatible solute metabolism and transport and new insights gained from studying marine bacteria belonging to the family .

细菌已经进化出一些机制，使它们能够适应渗透压的变化，并且一些物种已经适应在高盐度环境（如海洋生态系统）中最佳地生存。大多数生活在高盐度环境中的细菌是通过合成和/或摄取相容性溶质来实现的，相容性溶质是维持细胞膨压的小有机分子。海洋异养细菌中的渗透应激反应机制及其调控目前还知之甚少。在这篇综述中，我们讨论了关于相容性溶质代谢和运输的已知信息，以及从对属于该科的海洋细菌的研究中获得的新见解。