• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

压力之下:细菌利用相容性溶质生物合成和摄取系统对高盐度的响应及启示

Stressed out: Bacterial response to high salinity using compatible solute biosynthesis and uptake systems, lessons from .

作者信息

Gregory Gwendolyn J, Boyd E Fidelma

机构信息

Department of Biological Sciences, University of Delaware, Newark, DE 19716, United States.

出版信息

Comput Struct Biotechnol J. 2021 Feb 1;19:1014-1027. doi: 10.1016/j.csbj.2021.01.030. eCollection 2021.

DOI:10.1016/j.csbj.2021.01.030
PMID:33613867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7876524/
Abstract

Bacteria have evolved mechanisms that allow them to adapt to changes in osmolarity and some species have adapted to live optimally in high salinity environments such as in the marine ecosystem. Most bacteria that live in high salinity do so by the biosynthesis and/or uptake of compatible solutes, small organic molecules that maintain the turgor pressure of the cell. Osmotic stress response mechanisms and their regulation among marine heterotrophic bacteria are poorly understood. In this review, we discuss what is known about compatible solute metabolism and transport and new insights gained from studying marine bacteria belonging to the family .

摘要

细菌已经进化出一些机制,使它们能够适应渗透压的变化,并且一些物种已经适应在高盐度环境(如海洋生态系统)中最佳地生存。大多数生活在高盐度环境中的细菌是通过合成和/或摄取相容性溶质来实现的,相容性溶质是维持细胞膨压的小有机分子。海洋异养细菌中的渗透应激反应机制及其调控目前还知之甚少。在这篇综述中,我们讨论了关于相容性溶质代谢和运输的已知信息,以及从对属于该科的海洋细菌的研究中获得的新见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/537e/7876524/34d920198f36/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/537e/7876524/dc1759e3d85d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/537e/7876524/0348a8e1d4b7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/537e/7876524/245652192374/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/537e/7876524/e50ec697a1e8/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/537e/7876524/34d920198f36/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/537e/7876524/dc1759e3d85d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/537e/7876524/0348a8e1d4b7/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/537e/7876524/245652192374/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/537e/7876524/e50ec697a1e8/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/537e/7876524/34d920198f36/gr5.jpg

相似文献

1
Stressed out: Bacterial response to high salinity using compatible solute biosynthesis and uptake systems, lessons from .压力之下:细菌利用相容性溶质生物合成和摄取系统对高盐度的响应及启示
Comput Struct Biotechnol J. 2021 Feb 1;19:1014-1027. doi: 10.1016/j.csbj.2021.01.030. eCollection 2021.
2
CosR Is a Global Regulator of the Osmotic Stress Response with Widespread Distribution among Bacteria.CosR 是一种普遍存在于细菌中的渗透压应激反应的全局调控因子。
Appl Environ Microbiol. 2020 May 5;86(10). doi: 10.1128/AEM.00120-20.
3
Investigations of Dimethylglycine, Glycine Betaine, and Ectoine Uptake by a Betaine-Carnitine-Choline Transporter Family Transporter with Diverse Substrate Specificity in Species.物种中海藻糖胺、甘氨酸甜菜碱和章鱼胺摄取的研究 具有不同底物特异性的甜菜碱-肉碱-胆碱转运蛋白家族转运体
J Bacteriol. 2020 Nov 19;202(24). doi: 10.1128/JB.00314-20.
4
Quorum Sensing Regulators AphA and OpaR Control Expression of the Operon Responsible for Biosynthesis of the Compatible Solute Ectoine.群体感应调节子 AphA 和 OpaR 控制负责合成相容溶质章鱼胺的操纵子的表达。
Appl Environ Microbiol. 2019 Oct 30;85(22). doi: 10.1128/AEM.01543-19. Print 2019 Nov 15.
5
Biosynthesis of the osmoprotectant ectoine, but not glycine betaine, is critical for survival of osmotically stressed Vibrio parahaemolyticus cells.渗透胁迫下副溶血弧菌细胞的存活依赖于渗透物ectoine 的生物合成,但不依赖于甘氨酸甜菜碱。
Appl Environ Microbiol. 2013 Aug;79(16):5038-49. doi: 10.1128/AEM.01008-13. Epub 2013 Jun 14.
6
OpuF, a New Bacillus Compatible Solute ABC Transporter with a Substrate-Binding Protein Fused to the Transmembrane Domain.OpuF,一种新型与芽孢杆菌相容的 ABC 转运蛋白,其跨膜结构域融合了一个底物结合蛋白。
Appl Environ Microbiol. 2018 Oct 1;84(20). doi: 10.1128/AEM.01728-18. Print 2018 Oct 15.
7
The organosulfur compound dimethylsulfoniopropionate (DMSP) is utilized as an osmoprotectant by species.有机硫化合物二甲基巯基丙酸内盐(DMSP)被多种物种用作渗透保护剂。
Appl Environ Microbiol. 2021 Mar 1;87(5). doi: 10.1128/AEM.02235-20. Epub 2020 Dec 18.
8
Osmotic stress response of the coral and oyster pathogen : acquisition of catabolism gene clusters for the compatible solute and signaling molecule -inositol.珊瑚和牡蛎病原体的渗透胁迫反应:获得相容溶质和信号分子——肌醇的分解代谢基因簇。
Appl Environ Microbiol. 2024 Jul 24;90(7):e0092024. doi: 10.1128/aem.00920-24. Epub 2024 Jun 14.
9
Marinococcus halophilus DSM 20408T encodes two transporters for compatible solutes belonging to the betaine-carnitine-choline transporter family: identification and characterization of ectoine transporter EctM and glycine betaine transporter BetM.嗜盐海球菌DSM 20408T编码两种属于甜菜碱-肉碱-胆碱转运蛋白家族的相容性溶质转运蛋白:ectoine转运蛋白EctM和甘氨酸甜菜碱转运蛋白BetM的鉴定与特性分析。
Extremophiles. 2004 Jun;8(3):175-84. doi: 10.1007/s00792-004-0375-6. Epub 2004 Feb 11.
10
Osmotic stress response of the coral and oyster pathogen : acquisition of catabolism gene clusters for the compatible solute and signaling molecule -inositol.珊瑚和牡蛎病原体的渗透应激反应:获取用于相容性溶质和信号分子——肌醇的分解代谢基因簇
bioRxiv. 2024 May 8:2024.01.16.575920. doi: 10.1101/2024.01.16.575920.

引用本文的文献

1
Enhancement of environmental microplastics (MPs) degradation via bacteria under stress conditions: key enzymes, pathways, and mechanisms.压力条件下细菌对环境中微塑料(MPs)降解的增强作用:关键酶、途径及机制
World J Microbiol Biotechnol. 2025 Aug 26;41(9):318. doi: 10.1007/s11274-025-04525-1.
2
Genomic adaptations of Vibrio campbellii to thermal and salinity stress: insights into marine pathogen resilience in a changing ocean.坎氏弧菌对温度和盐度胁迫的基因组适应性:对不断变化的海洋中海洋病原体恢复力的见解。
BMC Genomics. 2025 Aug 8;26(1):736. doi: 10.1186/s12864-025-11908-z.
3
Genomic Insights and Plant Growth-Promoting Characterization of Strain 53B2, Isolated from Maize-Associated Soil in the Yaqui Valley, Mexico.

本文引用的文献

1
The organosulfur compound dimethylsulfoniopropionate (DMSP) is utilized as an osmoprotectant by species.有机硫化合物二甲基巯基丙酸内盐(DMSP)被多种物种用作渗透保护剂。
Appl Environ Microbiol. 2021 Mar 1;87(5). doi: 10.1128/AEM.02235-20. Epub 2020 Dec 18.
2
Bacteria are important dimethylsulfoniopropionate producers in marine aphotic and high-pressure environments.细菌是海洋无光和高压环境中重要的二甲基巯基丙酸内盐生产者。
Nat Commun. 2020 Sep 16;11(1):4658. doi: 10.1038/s41467-020-18434-4.
3
Genome Mining Reveals the Biosynthetic Pathways of Polyhydroxyalkanoate and Ectoines of the Halophilic Strain Salinivibrio proteolyticus M318 Isolated from Fermented Shrimp Paste.
从墨西哥亚基河谷与玉米相关的土壤中分离出的53B2菌株的基因组洞察及植物促生特性分析
Plants (Basel). 2025 Jul 7;14(13):2081. doi: 10.3390/plants14132081.
4
Salinization alters microbial methane cycling in freshwater sediments.盐渍化改变了淡水沉积物中的微生物甲烷循环。
Environ Microbiome. 2025 Jun 17;20(1):73. doi: 10.1186/s40793-025-00739-w.
5
Culture-supported ecophysiology of the SAR116 clade demonstrates metabolic and spatial niche partitioning.SAR116进化枝的培养支持生态生理学表明了代谢和空间生态位划分。
ISME J. 2025 Jan 2;19(1). doi: 10.1093/ismejo/wraf124.
6
Efficient Separation of a Novel Microbial Chassis, , from High-Salt Culture Broth Using Ceramic Ultrafiltration Membranes.使用陶瓷超滤膜从高盐培养液中高效分离新型微生物底盘。
Membranes (Basel). 2025 Apr 11;15(4):121. doi: 10.3390/membranes15040121.
7
Dual roles of glycine betaine, dimethylglycine, and sarcosine as osmoprotectants and nutrient sources for .甘氨酸甜菜碱、二甲基甘氨酸和肌氨酸作为渗透保护剂和……的营养源的双重作用
Appl Environ Microbiol. 2025 May 21;91(5):e0061925. doi: 10.1128/aem.00619-25. Epub 2025 Apr 23.
8
Genomic highlights of the phylogenetically unique halophilic purple nonsulfur bacterium, Rhodothalassium salexigens.系统发育上独特的嗜盐紫色非硫细菌——盐生红钾菌的基因组亮点
Extremophiles. 2025 Jan 25;29(1):12. doi: 10.1007/s00792-025-01380-8.
9
Maize drought protection by Azospirillum argentinense Az19 requires bacterial trehalose accumulation.阿根廷固氮螺菌Az19对玉米的干旱保护作用需要细菌积累海藻糖。
Appl Microbiol Biotechnol. 2024 Dec 27;108(1):543. doi: 10.1007/s00253-024-13391-0.
10
Genome-wide analysis of quorum sensing regulon in marine fish pathogen Vibrio scophthalmi.海洋鱼类病原菌鳗弧菌群体感应调控子的全基因组分析。
Sci Rep. 2024 Nov 12;14(1):27740. doi: 10.1038/s41598-024-78803-7.
基因组挖掘揭示了从发酵虾酱中分离的嗜盐菌 Salinivibrio proteolyticus M318 中聚羟基烷酸酯和胞外多胺的生物合成途径。
Mar Biotechnol (NY). 2020 Oct;22(5):651-660. doi: 10.1007/s10126-020-09986-z. Epub 2020 Aug 22.
4
Investigations of Dimethylglycine, Glycine Betaine, and Ectoine Uptake by a Betaine-Carnitine-Choline Transporter Family Transporter with Diverse Substrate Specificity in Species.物种中海藻糖胺、甘氨酸甜菜碱和章鱼胺摄取的研究 具有不同底物特异性的甜菜碱-肉碱-胆碱转运蛋白家族转运体
J Bacteriol. 2020 Nov 19;202(24). doi: 10.1128/JB.00314-20.
5
The ups and downs of ectoine: structural enzymology of a major microbial stress protectant and versatile nutrient.依克多因的起伏:一种主要的微生物应激保护剂和多功能营养素的结构酶学
Biol Chem. 2020 Nov 26;401(12):1443-1468. doi: 10.1515/hsz-2020-0223.
6
Role of ,-Dimethylglycine and Its Catabolism to Sarcosine in Chromohalobacter salexigens DSM 3043.色盐杆菌 DSM 3043 中 -二甲基甘氨酸及其代谢为肌氨酸的作用。
Appl Environ Microbiol. 2020 Aug 18;86(17). doi: 10.1128/AEM.01186-20.
7
The osmotic stress response operon betIBA is under the functional regulation of BetI and the quorum-sensing regulator AnoR in Acinetobacter nosocomialis.耐碳青霉烯鲍曼不动杆菌的渗透胁迫反应操纵子 betIBA 受 BetI 和群体感应调节因子 AnoR 的功能调控。
J Microbiol. 2020 Jun;58(6):519-529. doi: 10.1007/s12275-020-0186-1. Epub 2020 May 27.
8
Degradation of the microbial stress protectants and chemical chaperones ectoine and hydroxyectoine by a bacterial hydrolase-deacetylase complex.细菌水解脱乙酰酶复合物对微生物应激保护剂和化学伴侣ectoine 和 hydroxyectoine 的降解作用。
J Biol Chem. 2020 Jul 3;295(27):9087-9104. doi: 10.1074/jbc.RA120.012722. Epub 2020 May 13.
9
DMSP-Producing Bacteria Are More Abundant in the Surface Microlayer than Subsurface Seawater of the East China Sea.东海表层海水中的产 DMSP 细菌比底层海水中更丰富。
Microb Ecol. 2020 Aug;80(2):350-365. doi: 10.1007/s00248-020-01507-8. Epub 2020 Apr 25.
10
Identification of osmo-dependent and osmo-independent betaine-choline-carnitine transporters in Acinetobacter baumannii: role in osmostress protection and metabolic adaptation.在鲍曼不动杆菌中鉴定出渗透依赖型和渗透非依赖型甜菜碱-胆碱-肉碱转运体:在渗透压应激保护和代谢适应中的作用。
Environ Microbiol. 2020 Jul;22(7):2724-2735. doi: 10.1111/1462-2920.14998. Epub 2020 Apr 6.