Vera Nieves Bryan, Lindblad Geoffrey, Gupta Javas, Hughes Jessica, Rivero Andres
Infectious Disease, Aventura Hospital and Medical Center, Miami, USA.
Radiology, Aventura Hospital and Medical Center, Miami, USA.
Cureus. 2021 Jan 15;13(1):e12728. doi: 10.7759/cureus.12728.
Lemierre's syndrome is an oropharyngeal infection complicated by septic thrombophlebitis of the internal jugular vein, bacteremia, and septic emboli. It mainly occurs in immunocompetent individuals and was first reported in the early 1900s by physician Andre Lemierre. A 23-year-old male presented to our institution with sore throat, difficulty swallowing, left-sided ear pain, nausea, vomiting, subjective fevers, general malaise, right-sided rib pain, and anorexia. Complete blood cell count and metabolic panels revealed severe thrombocytopenia, mild anemia, acute kidney injury, and hyperbilirubinemia. Blood cultures grew . Ultrasound and computed tomography scan of the neck revealed thrombosis of the left internal jugular vein. ADAMTS13 activity was later reported to be markedly decreased at less than 2%, confirming a diagnosis of thrombotic thrombocytopenic purpura.
勒米尔综合征是一种口咽感染，并发颈内静脉脓毒性血栓形成、菌血症和脓毒性栓子。它主要发生在免疫功能正常的个体中，最早于20世纪初由内科医生安德烈·勒米尔报道。一名23岁男性因咽痛、吞咽困难、左耳疼痛、恶心、呕吐、自觉发热、全身不适、右肋疼痛和厌食前来我院就诊。全血细胞计数和代谢指标显示严重血小板减少、轻度贫血、急性肾损伤和高胆红素血症。血培养生长出……颈部超声和计算机断层扫描显示左颈内静脉血栓形成。后来报告ADAMTS13活性显著降低，低于2%，确诊为血栓性血小板减少性紫癜。
