Muhammad Haris, Santhanam Prasanna, Russell Jonathon O, Kuo Jennifer H
Department of Internal Medicine Greater Baltimore Medical Center Towson Maryland USA.
Division of Endocrinology, Diabetes, & Metabolism, Department of Medicine Johns Hopkins University School of Medicine Baltimore Maryland USA.
Laryngoscope Investig Otolaryngol. 2021 Jan 9;6(1):155-165. doi: 10.1002/lio2.517. eCollection 2021 Feb.
Benign thyroid nodules (BTNs) are commonly found in the general population. They are usually asymptomatic and their incidence has increased as a result of wide-spread use of ultrasound. Benign nodules are typically monitored clinically until they increase in size, resulting in compressive symptoms warranting surgery. However, although surgery is generally well-tolerated and of low-risk, it is associated with a small risk for several complications including hypothyroidism, nerve injury, hematoma, injury to other structures and wound infection. Recently, newer image-guided ablation techniques including radiofrequency ablation (RFA) have been introduced. RFA has a similar safety profile when compared to surgery and has shown promising results in challenging surgical candidates. Though several studies have been published in Asian and European countries on the efficacy of RFA, limited data is available on the North American population. The aim of the study is to review the current literature establishing the clinical outcomes and safety of RFA for benign nodules.
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良性甲状腺结节（BTNs）在普通人群中很常见。它们通常无症状，由于超声的广泛应用，其发病率有所增加。良性结节通常在临床上进行监测，直到其大小增加，导致出现需要手术的压迫症状。然而，尽管手术一般耐受性良好且风险较低，但它与包括甲状腺功能减退、神经损伤、血肿、其他结构损伤和伤口感染在内的几种并发症的小风险相关。最近，包括射频消融（RFA）在内的更新的图像引导消融技术已经被引入。与手术相比，RFA具有相似的安全性，并且在具有挑战性的手术候选者中显示出有前景的结果。尽管亚洲和欧洲国家已经发表了几项关于RFA疗效的研究，但关于北美人群的数据有限。该研究的目的是回顾当前文献，确立RFA治疗良性结节的临床结果和安全性。
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