Brüne Manuela, Emmel Carina, Meilands Gisela, Andrich Silke, Droste Sigrid, Claessen Heiner, Jülich Fabian, Icks Andrea
Institute for Health Services Research and Health Economics, Centre for Health and Society, Faculty of Medicine, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Institute for Health Services Research and Health Economics, German Diabetes Center, Leibniz Center for Diabetes Research at the Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany.
Pharmacoepidemiol Drug Saf. 2021 May;30(5):531-560. doi: 10.1002/pds.5210. Epub 2021 Mar 5.
To identify and describe publications addressing the agreement between self-reported medication and other data sources among adults and, in a subgroup of studies dealing with cancer patients, seek to identify parameters which are associated with agreement.
A systematic review including a systematic search within five biomedical databases up to February 28, 2019 was conducted as per the PRISMA Statement. Studies and agreement results were described. For a subgroup of studies dealing with cancer, we searched for associations between agreement and patients' characteristics, study design, comparison data source, and self-report modality.
The literature search retrieved 3392 publications. Included articles (n = 120) show heterogeneous agreement. Eighteen publications focused on cancer populations, with relatively good agreement identified in those which analyzed hormone therapy, estrogen, and chemotherapy (n = 11). Agreement was especially good for chemotherapy (proportion correct ≥93.6%, kappa ≥0.88). No distinct associations between agreement and age, education or marital status were identified in the results. There was little evaluation of associations between agreement and study design, self-report modality and comparison data source, thus not allowing for any conclusions to be drawn.
An overview of the evidence available from validation studies with a description of several characteristics is provided. Studies with experimental design which evaluate factors that might affect agreement between self-report and other data sources are lacking.
识别并描述针对成年人自我报告用药情况与其他数据来源之间一致性的出版物，并在涉及癌症患者的研究亚组中，试图识别与一致性相关的参数。
按照PRISMA声明，进行了一项系统评价，包括截至2019年2月28日在五个生物医学数据库内进行系统检索。描述了研究及一致性结果。对于涉及癌症的研究亚组，我们搜索了一致性与患者特征、研究设计、比较数据源及自我报告方式之间的关联。
文献检索共获取3392篇出版物。纳入的文章（n = 120）显示出异质性的一致性。18篇出版物聚焦于癌症人群，在分析激素治疗、雌激素和化疗的研究中发现了相对较好的一致性（n = 11）。化疗的一致性尤其好（正确比例≥93.6%，kappa≥0.88）。结果中未发现一致性与年龄、教育程度或婚姻状况之间存在明显关联。对一致性与研究设计、自我报告方式和比较数据源之间的关联评估较少，因此无法得出任何结论。
提供了来自验证研究的证据概述，并描述了几个特征。缺乏采用实验设计来评估可能影响自我报告与其他数据来源之间一致性的因素的研究。
