Department of Preventive Medicine and Institute of Health Services Research, Yonsei University College of Medicine, Seoul, Korea.
J Prev Med Public Health. 2021 Jan;54(1):63-72. doi: 10.3961/jpmph.20.315. Epub 2020 Dec 30.
Recent studies have suggested that assessing handgrip strength (HGS) asymmetry together with HGS may be helpful for evaluating problems in geriatric patients. This study aimed to identify whether HGS asymmetry, weakness, or both were associated with depression in Korean older adults.
This study included 4274 subjects from the sixth and seventh Korea National Health and Nutrition Examination Survey. Depression was measured using the Patient Health Questionnaire-9. The maximum HGS of the dominant hand was used as a representative value. HGS symmetry was categorized by the ratio of the HGS of the dominant hand to that of non-dominant hand. The odds ratio (OR) for depression was calculated according to the HGS and its symmetry.
In total, 240 (12.5%) men and 534 (22.7%) women had depression. HGS or HGS asymmetry showed no statistically significant associations with depression in elderly men. Elevated odds of depression were observed in elderly women with low HGS (OR, 1.93; 95% confidence interval [CI], 1.33 to 2.81) or prominent HGS asymmetry (OR, 1.46; 95% CI, 1.02 to 2.08). There was a positive additive interaction between asymmetric HGS and weakness, as women with low and prominently asymmetric HGS showed higher odds of depression (OR, 3.77; 95% CI, 2.16 to 6.59) than women with high and symmetric HGS.
Depression in elderly Korean women was associated with both low and asymmetric HGS. Our findings support the potential value of HGS asymmetry as an indicator of HGS.
最近的研究表明，评估握力（HGS）不对称性与 HGS 相结合可能有助于评估老年患者的问题。本研究旨在确定 HGS 不对称性、虚弱或两者是否与韩国老年人的抑郁有关。
本研究纳入了第六届和第七届韩国国家健康与营养调查的 4274 名受试者。使用患者健康问卷-9 测量抑郁。将惯用手的最大 HGS 用作代表值。根据惯用手与非惯用手的 HGS 比值对 HGS 对称性进行分类。根据 HGS 及其对称性计算抑郁的优势比（OR）。
共有 240 名（12.5%）男性和 534 名（22.7%）女性患有抑郁。在老年男性中，HGS 或 HGS 不对称性与抑郁无统计学显著相关性。在 HGS 水平较低（OR，1.93；95%置信区间[CI]，1.33 至 2.81）或 HGS 明显不对称（OR，1.46；95%CI，1.02 至 2.08）的老年女性中，抑郁的几率升高。不对称 HGS 与虚弱之间存在正相加交互作用，因为 HGS 水平低且明显不对称的女性比 HGS 水平高且对称的女性患抑郁的几率更高（OR，3.77；95%CI，2.16 至 6.59）。
韩国老年女性的抑郁与低 HGS 和不对称性有关。我们的研究结果支持 HGS 不对称性作为 HGS 指标的潜在价值。
