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感染性全膝关节置换的诊断与处理:实用外科指南

Diagnosis and management of the infected total knee replacement: a practical surgical guide.

作者信息

Zahar Akos, Sarungi Martin

机构信息

Department of Orthopaedic & Trauma Surgery, Helios Klinikum Emil von Behring, Walterhöferstrasse 11, 14165, Berlin, Germany.

Orthopaedic Department, The Golden Jubilee National Hospital, Glasgow, Scotland, UK.

出版信息

J Exp Orthop. 2021 Feb 22;8(1):14. doi: 10.1186/s40634-021-00333-2.

Abstract

PURPOSE

Prosthetic joint infection (PJI) after total knee arthroplasty (TKA) is a significant burden in health care. Diagnosis and proper management are challenging. A standardised procedure for the diagnostic workup and surgical management provides clear benefits in outcome.

METHODS

Several diagnostic protocols and definitions for PJI were established in recent years. Proper PJI diagnosis remains critical for success and for choosing the optimal treatment option. A distinct workup of diagnostic steps, the evaluation of the results in a multidisciplinary setup and the meticulous surgical management of the infection are the key factors of successful treatment.

RESULTS

The management of PJI after TKA consists of early revision with debridement and implant retention (DAIR) in early cases or staged revision in late infections beyond 30 days postoperative or after onset of acute symptoms. The revision is performed as a two-stage procedure with the use of a fixed or mobile antibiotic spacer, or in selected cases as a single-stage operation with the use of local and systemic antibiotic treatment.

CONCLUSIONS

This paper reflects the opinion of two revision surgeons who follow the same protocol for diagnosis and treatment of PJI after TKA, highlighting the key steps in diagnosis and management.

LEVEL OF EVIDENCE

Expert's opinion.

摘要

目的

全膝关节置换术(TKA)后假体关节感染(PJI)是医疗保健中的一项重大负担。诊断和妥善管理具有挑战性。标准化的诊断检查和手术管理程序在治疗结果方面具有明显优势。

方法

近年来制定了几种PJI的诊断方案和定义。正确的PJI诊断对于成功以及选择最佳治疗方案仍然至关重要。明确的诊断步骤检查、多学科环境下对结果的评估以及对感染的精心手术管理是成功治疗的关键因素。

结果

TKA后PJI的管理包括在早期病例中进行清创和保留植入物的早期翻修(DAIR),或在术后30天以上的晚期感染或急性症状出现后进行分期翻修。翻修作为两阶段手术进行,使用固定或可移动抗生素间隔物,或在选定病例中作为单阶段手术,使用局部和全身抗生素治疗。

结论

本文反映了两位翻修外科医生对于TKA后PJI的诊断和治疗遵循相同方案的观点,突出了诊断和管理的关键步骤。

证据水平

专家意见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12ee/7900357/400ad5d9d40d/40634_2021_333_Fig1_HTML.jpg

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