父母对发育状况的评估（PEDS）、PEDS发育里程碑及PEDS综合评估对印度2岁以下儿童的诊断准确性

Diagnostic Accuracy of Parents' Evaluation of Developmental Status (PEDS), PEDS Developmental Milestones, and PEDS Combined in Indian Children Aged Less than 2 Years.

作者信息

Mukherjee Sharmila Banerjee, Verma Sangeeta, Sharma Suvasini, Aneja Satinder

机构信息

Department of Pediatrics, Lady Hardinge Medical College and Associated Kalawati Saran Children's Hospital, Bangla Sahib Road, New Delhi, 110001, India.

出版信息

Indian J Pediatr. 2022 May;89(5):459-465. doi: 10.1007/s12098-020-03651-y. Epub 2021 Feb 23.

DOI:10.1007/s12098-020-03651-y

PMID:33620632

Abstract

OBJECTIVE

To assess the diagnostic accuracy of Parent's Evaluation of Developmental Status (PEDS), PEDS Developmental Milestones (PEDS:DM) and PEDS Combined for developmental screening of Indian children aged less than 2 y.

METHOD

A hospital-based study of diagnostic accuracy was conducted over 17 mo. Children under 24 mo (n = 180) were enrolled after exclusion of severe illnesses or known neurodevelopment disorders. The index tools included standardized Hindi translations of PEDS and PEDS:DM. The reference tool was Developmental Assessment Scale for Indian Infants (DASII). Both were administered by blinded researchers. Parameters of diagnostic accuracy were computed.

RESULTS

There were 13 (7.2%) failures in PEDS, 119 (66.1%) in PEDS:DM and 119 (66.1%) in PEDS Combined. DASII identified 3 children with developmental delay. Sensitivity (Sn) [95% CI] of PEDS was 33.3 [0.8-90.6] and Specificity (Sp) 93.2 [88.5-96.5]. The Sn and Sp of both PEDS:DM and PEDS Combined were 100 [29.2-100] and 34.5 [27.5-42.0], respectively.

CONCLUSIONS

Hindi translations of PEDS, PEDS:DM and PEDS Combined are not suitable for developmental screening of children less than 2 y due to suboptimal diagnostic accuracy.

摘要

目的

评估父母发育状况评估量表（PEDS）、PEDS发育里程碑量表（PEDS:DM）及PEDS综合量表对2岁以下印度儿童进行发育筛查的诊断准确性。

方法

进行了一项为期17个月的基于医院的诊断准确性研究。排除重症疾病或已知神经发育障碍后，纳入24个月以下儿童（n = 180）。指标工具包括PEDS和PEDS:DM的印地语标准化译本。参考工具为印度婴儿发育评估量表（DASII）。二者均由不知情的研究人员实施。计算诊断准确性参数。

结果

PEDS有13例（7.2%）筛查失败，PEDS:DM有119例（66.1%），PEDS综合量表有119例（66.1%）。DASII识别出3例发育迟缓儿童。PEDS的灵敏度（Sn）[95%可信区间]为33.3 [0.8 - 90.6]，特异度（Sp）为93.2 [88.5 - 96.5]。PEDS:DM和PEDS综合量表的Sn和Sp分别为100 [29.2 - 100]和34.5 [27.5 - 42.0]。