Paulin C, Dubois M P, Barry J, Dubois P M
Cell Tissue Res. 1977 Aug 26;182(3):341-5. doi: 10.1007/BF00219769.
The use of antibodies to synthetic LH-RH has enabled the detection by immunofluorescence of hypothalamic LH-RH producing cells in the human fetus. The perikarya of these cells are located in the pericommissural and peroptic regions, in the lamina terminalis and in the premamillary region. Reactive axons occur in the median eminence. The first LH-RH producing cells are seen as early as nine weeks of gestation. The specificity of immunocytological reaction has been controlled.
使用针对合成促黄体激素释放激素（LH-RH）的抗体，能够通过免疫荧光检测出人类胎儿下丘脑产生LH-RH的细胞。这些细胞的胞体位于连合周和视周区域、终板以及乳头前区域。反应性轴突出现在正中隆起。最早在妊娠九周时就能看到产生LH-RH的细胞。免疫细胞反应的特异性已经得到验证。
