Paulin C, Dubois P M, Czernichow P, Dubois M P
Cell Tissue Res. 1978 Apr 17;188(2):259-64. doi: 10.1007/BF00222635.
The use of antibodies against oxytocin or neurophysin enabled the detection by immunocytochemistry of oxytocin-neurophysin neurons in the hypothalamus in the human fetus. The perikarya of these neurons are located in the paraventricular and supraoptic nuclei. Immunoreactive neurons occure in the median eminence. The neurophysin immunoreactive neurons were more numerous than the oxytocin immunoreactive neurons. The specificity of the immunocytological reaction was controlled. The first oxytocin-neurophysin neurons are seen as early as the 14th week of gestation.
使用抗催产素或神经垂体素的抗体，通过免疫细胞化学方法能够检测到人类胎儿下丘脑内的催产素 - 神经垂体素神经元。这些神经元的胞体位于室旁核和视上核。免疫反应性神经元出现在正中隆起。神经垂体素免疫反应性神经元比催产素免疫反应性神经元数量更多。免疫细胞反应的特异性得到了验证。最早在妊娠第14周就能看到催产素 - 神经垂体素神经元。
