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撒哈拉以南非洲地区药品定价政策的实施:一项系统评价方案

Implementation of medicines pricing policies in sub-Saharan Africa: protocol for a systematic review.

作者信息

Mirzoev Tolib, Koduah Augustina, Cronin de Chavez Anna, Baatiema Leonard, Danso-Appiah Anthony, Ensor Tim, Agyepong Irene Akua, Wright Judy M, Kretchy Irene A, King Natalie

机构信息

Nuffield Centre for International Health and Development, University of Leeds, Leeds, West Yorkshire, UK

School of Pharmacy, University of Ghana, Legon, Greater Accra, Ghana.

出版信息

BMJ Open. 2021 Feb 23;11(2):e044293. doi: 10.1136/bmjopen-2020-044293.

Abstract

INTRODUCTION

Ensuring universal availability and accessibility of medicines and supplies is critical for national health systems to equitably address population health needs. In sub-Saharan Africa (SSA), this is a recognised priority with multiple medicines pricing policies enacted. However, medicine prices have remained high, continue to rise and constrain their accessibility. In this systematic review, we aim to identify and analyse experiences of implementation of medicines pricing policies in SSA. Our ambition is for this evidence to contribute to improved implementation of medicines pricing policies in SSA.

METHODS AND ANALYSIS

We will search: Medline, Web of Science, Scopus, Global Health, Embase, Cairn.Info International Edition, Erudit and African Index Medicus, the grey literature and reference from related publications. The searches will be limited to literature published from the year 2000 onwards that is, since the start of the Millennium Development Goals.Published peer-reviewed studies of implementation of medicines pricing policies in SSA will be eligible for inclusion. Broader policy analyses and documented experiences of implementation of other health policies will be excluded. The team will collaboratively screen titles and abstracts, then two reviewers will independently screen full texts, extract data and assess quality of the included studies. Disagreements will be resolved by discussion or a third reviewer. Data will be extracted on approaches used for policy implementation, actors involved, evidence used in decision making and key contextual influences on policy implementation. A narrative approach will be used to synthesise the data. Reporting will be informed by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols guideline.

ETHICS AND DISSEMINATION

No ethics approvals are required for systematic reviews.Results will be disseminated through academic publications, policy briefs and presentations to national policymakers in Ghana and mode widely across countries in SSA.

PROSPERO REGISTRATION NUMBER

CRD42020178166.

摘要

引言

确保药品和物资的普遍可获得性及可及性,对于国家卫生系统公平满足民众健康需求至关重要。在撒哈拉以南非洲地区(SSA),这是一个公认的优先事项,已制定了多项药品定价政策。然而,药品价格一直居高不下,且持续上涨,限制了其可及性。在本系统评价中,我们旨在识别和分析SSA地区药品定价政策的实施经验。我们的目标是,这些证据有助于改善SSA地区药品定价政策的实施情况。

方法与分析

我们将检索:Medline、科学引文索引、Scopus、《全球健康》、Embase、Cairn.Info国际版、Erudit以及《非洲医学索引》、灰色文献和相关出版物的参考文献。检索将限于2000年起发表的文献,即自千年发展目标启动以来的文献。已发表的关于SSA地区药品定价政策实施情况的同行评审研究将符合纳入条件。更广泛的政策分析以及其他卫生政策实施情况的记录经验将被排除。研究团队将共同筛选标题和摘要,然后两名评审员将独立筛选全文、提取数据并评估纳入研究的质量。分歧将通过讨论或由第三位评审员解决。将提取有关政策实施所采用的方法、涉及的行为主体、决策中使用的证据以及对政策实施的关键背景影响的数据。将采用叙述性方法对数据进行综合。报告将遵循系统评价和Meta分析方案的首选报告项目指南。

伦理与传播

系统评价无需伦理批准。结果将通过学术出版物、政策简报以及向加纳国家政策制定者的汇报进行传播,并更广泛地传播到SSA地区的各个国家。

PROSPERO注册号:CRD42020178166。

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