Rajawat Akansha, Majeti Chandrakanth, Podugu Uday Kumar, Kaushik Mamta, Nagamaheshwari X, Mehra Neha
Department of Conservative Dentistry and Endodontics, Army College of Dental Sciences, Secunderabad, Telangana, India.
J Conserv Dent. 2020 Jul-Aug;23(4):337-340. doi: 10.4103/JCD.JCD_367_20. Epub 2021 Jan 16.
Dental caries remains the most widespread oral disease among all age groups. Hormonal fingerprints (second digit: fourth digit ratio or 2D:4D ratio) are biomarkers displaying sexual dimorphism and diverse human phenotypic traits. A person's genetic makeup may influence the occurrence of dental caries.
The present study aimed to evaluate the influence of digit ratio on the incidence of dental caries.
Two hundred patients between 18 and 55 years, reporting for restorations or endodontic therapy, participated in the study.
Hormonal fingerprints (2D:4D ratio) were measured with the help of a digital vernier caliper. Caries incidence was recorded using the DMFT index.
Data obtained were tabulated and statistically analyzed using Independent -test and Chi-square test.
Males had a less mean 2D:4D ratio than females, which was statistically significant (-value = 0.003). Chi-square test was applied, and there was a statistically significant correlation between high digit ratio and caries experience (-value = 0.002). Females with a high digit ratio and males with a low digit ratio were in the moderate and low caries risk groups with a -value of 0.029 and 0.001 in the respective risk groups.
The present study displayed a correlation between hormonal fingerprints (2D:4D ratio) and dental caries. An indicator of caries risk will help prevent caries by implementing oral hygiene measures, which will reduce its incidence as the most occurring oral disease.
龋齿仍然是所有年龄组中最普遍的口腔疾病。激素指纹（食指与无名指长度比或2D:4D比）是显示性别二态性和多种人类表型特征的生物标志物。一个人的基因组成可能会影响龋齿的发生。
本研究旨在评估指长比与龋齿发病率之间的关系。
200名年龄在18至55岁之间、因修复或牙髓治疗前来就诊的患者参与了本研究。
借助数字游标卡尺测量激素指纹（2D:4D比）。使用DMFT指数记录龋齿发病率。
将获得的数据制成表格，并使用独立样本t检验和卡方检验进行统计分析。
男性的平均2D:4D比低于女性，差异具有统计学意义（P值 = 0.003）。应用卡方检验，高指长比与龋齿经历之间存在统计学显著相关性（P值 = 0.002）。高指长比的女性和低指长比的男性分别处于中度和低度龋齿风险组，各自风险组中的P值分别为0.029和0.001。
本研究显示激素指纹（2D:4D比）与龋齿之间存在相关性。龋齿风险指标将有助于通过实施口腔卫生措施预防龋齿，这将降低其作为最常见口腔疾病的发病率。
