Nandish B T, Jayaprakash K, Shetty Harish Kumar, Rao Sowmya, Ginjupalli Kishore, Chandrashekhar H Raghu, Prabhu Sudeendra
Department of Dental Materials, Yenepoya Dental College, Yenepoya (Deemed to be University), Mangalore, Karnataka, India.
Department of Dental Materials, Biomaterials and Research Centre, Yenepoya Dental College, Yenepoya (Deemed to be University), Mangalore, Karnataka, India.
J Conserv Dent. 2020 Jul-Aug;23(4):412-416. doi: 10.4103/JCD.JCD_260_20. Epub 2021 Jan 16.
In dentistry, base metal casting alloys are extensively used for the fabrication of inlays, onlays, crowns, bridges, partial dentures, etc. During the casting of these alloys, excess amount of material used than needed will be collected as sprue buttons at the end, which is either added to the fresh alloy during casting and reused or disposed of.
The aim of the present experimental study was to investigate the effect of the complete recasting of four commercially available cobalt-chromium (Co-Cr) and nickel-chromium (Ni-Cr) base metal casting alloys on their cytotoxicity. During the study, four groups of alloys were subjected to complete recasting up to twenty times without the addition of new alloy. The cytotoxicity assessment of the selected alloys after recasting (Co-Cr and Ni-Cr alloys) was carried out using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay.
The results indicated that Co-Cr alloys exhibit superior cell viability compared to Ni-Cr alloys, and cytotoxic potential of the alloys increased with repeated casting and led to increased cell death. The recasting of alloys in the present study did not show high cytotoxicity even after the 20 recasting.
From the results of the present study, it can be concluded that the alloys generated as a waste in the dental laboratory can be safely reused up to five times or at least once before they can be disposed, which reduces the cost of the treatment and also helps in conserving the natural resources.
在牙科领域,贱金属铸造合金广泛用于制作嵌体、高嵌体、冠、桥、局部义齿等。在这些合金铸造过程中,使用的材料超出所需量的部分最终会作为铸道桩被收集起来,这些铸道桩要么在铸造时添加到新合金中重新使用,要么被处理掉。
本实验研究的目的是调查四种市售钴铬(Co-Cr)和镍铬(Ni-Cr)贱金属铸造合金完全重铸对其细胞毒性的影响。在研究过程中,四组合金在不添加新合金的情况下进行了多达二十次的完全重铸。使用3-(4,5-二甲基噻唑-2-基)-2,5-二苯基四氮唑溴盐法对重铸后的选定合金(Co-Cr和Ni-Cr合金)进行细胞毒性评估。
结果表明,与Ni-Cr合金相比,Co-Cr合金表现出更高的细胞活力,并且合金的细胞毒性潜力随着重复铸造而增加,导致细胞死亡增加。即使在本研究中合金重铸20次后,重铸后的合金也未显示出高细胞毒性。
从本研究结果可以得出结论,牙科实验室产生的作为废物的合金在可以处理之前可以安全地重复使用多达五次或至少一次,这降低了治疗成本,也有助于保护自然资源。