基于强电子受体 2,2'-(蒽-9,10-二亚基)二丙二腈的聚集诱导发射荧光团，用于近红外二区的生物成像。
Aggregation-induced emission fluorophores based on strong electron-acceptor 2,2'-(anthracene-9,10-diylidene) dimalononitrile for biological imaging in the NIR-II window.
机构信息
Key Laboratory for Advanced Materials, Joint International Research Laboratory for Precision Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, P. R. China.
出版信息
Chem Commun (Camb). 2021 Mar 28;57(25):3099-3102. doi: 10.1039/d1cc00742d. Epub 2021 Feb 24.
In this communication, three novel donor-acceptor-donor type second near-infrared AIE fluorophores based on strong electron-acceptor 2,2'-(anthracene-9,10-diylidene) dimalononitrile have been successfully developed for bioimaging, in which they exhibit good photostability and can be used in mouse ear vessel imaging with high resolution (FWHM = 93.4 μm/SBR = 1.5) after capsuling in nanoparticles with good biocompatibility.
在本通讯中，设计并合成了三种新型给体-受体-给体型的近红外 AIE 荧光染料，基于强电子受体 2,2'-(蒽-9,10-二亚基)二丙二腈，用于生物成像。它们具有良好的光稳定性，在封装在具有良好生物相容性的纳米粒子后，可以在小鼠耳部血管成像中以高分辨率（FWHM = 93.4μm/SBR = 1.5）进行使用。
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