From the Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Columbia University College of Physicians and Surgeons/NewYork-Presbyterian Hospital, New York, New York.
Department of Surgery, Columbia University College of Physicians and Surgeons/NewYork-Presbyterian Hospital, New York, New York.
ASAIO J. 2021 Mar 1;67(3):245-249. doi: 10.1097/MAT.0000000000001376.
The coronavirus disease 2019 (COVID-19) pandemic has placed extraordinary strain on global healthcare systems. Use of extracorporeal membrane oxygenation (ECMO) for patients with severe respiratory or cardiac failure attributed to COVID-19 has been debated due to uncertain survival benefit and the resources required to safely deliver ECMO support. We retrospectively investigated adult patients supported with ECMO for COVID-19 at our institution during the first 80 days following New York City's declaration of a state of emergency. The primary objective was to evaluate survival outcomes in patients supported with ECMO for COVID-19 and describe the programmatic adaptations made in response to pandemic-related crisis conditions. Twenty-two patients with COVID-19 were placed on ECMO during the study period. Median age was 52 years and 18 (81.8%) were male. Twenty-one patients (95.4%) had severe ARDS and seven (31.8%) had cardiac failure. Fifteen patients (68.1%) were managed with venovenous ECMO while 7 (31.8%) required arterial support. Twelve patients (54.5%) were transported on ECMO from external institutions. Twelve patients were discharged alive from the hospital (54.5%). Extracorporeal membrane oxygenation was used successfully in patients with respiratory and cardiac failure due to COVID-19. The continued use of ECMO, including ECMO transport, during crisis conditions was possible even at the height of the COVID-19 pandemic.
新型冠状病毒病 2019(COVID-19)大流行给全球医疗体系带来了巨大压力。由于对 COVID-19 导致的严重呼吸或心脏衰竭患者的生存获益不确定,以及安全提供 ECMO 支持所需的资源,因此对使用体外膜肺氧合(ECMO)存在争议。我们对纽约市宣布进入紧急状态后的头 80 天内我院接受 ECMO 支持的 COVID-19 成年患者进行了回顾性研究。主要目的是评估 COVID-19 患者接受 ECMO 支持的生存结果,并描述针对大流行相关危机情况所做出的计划调整。研究期间,22 例 COVID-19 患者接受 ECMO 治疗。中位年龄为 52 岁,18 例(81.8%)为男性。21 例(95.4%)患者患有严重的急性呼吸窘迫综合征,7 例(31.8%)患有心力衰竭。15 例患者(68.1%)采用静脉-静脉 ECMO 治疗,7 例(31.8%)需要动脉支持。12 例患者(54.5%)从外部机构转运至 ECMO 治疗。12 例患者(54.5%)从医院出院存活。体外膜肺氧合成功用于治疗因 COVID-19 导致的呼吸和心脏衰竭患者。即使在 COVID-19 大流行高峰期,也可以在危机情况下继续使用 ECMO,包括 ECMO 转运。