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埃塞俄比亚吉马市吉马医疗中心新生儿先天性异常的患病率及趋势:一项为期三年的回顾性研究

Prevalence and Trends of Congenital Anomalies Among Neonates at Jimma Medical Center, Jimma, Ethiopia: A Three-Year Retrospective Study.

作者信息

Silesh Mulualem, Lemma Tesfanesh, Fenta Belete, Biyazin Tsegaw

机构信息

Department of Midwifery, College of Health Science and Medicine, Debre Berhan University, Debre Berhan, Ethiopia.

School of Nursing and Midwifery, Institute of Health, Faculty of Health Sciences, Jimma University, Jimma, Ethiopia.

出版信息

Pediatric Health Med Ther. 2021 Feb 17;12:61-67. doi: 10.2147/PHMT.S293285. eCollection 2021.

Abstract

INTRODUCTION

Congenital anomalies are a major public health problem which is defined as structural or functional anomalies that occur during intrauterine life which can be detected prenatally, at birth, or sometimes may only be detected later in infancy. The impact of congenital anomalies is severe in middle- and low-income countries than in other developed and developing countries.

OBJECTIVE

To assess the prevalence and trends of congenital anomalies among neonates admitted at Jimma Medical Center from 2017 to 2019.

METHODS

A facility-based retrospective, descriptive crossectional study was conducted among neonates admitted at Jimma Medical Center from 2017-2019. Descriptive analysis (frequency and percentage) was calculated for the variables. The result was present in the table, text, and figure.

RESULTS

From a total of 3346 admitted neonates, 199 (5.95%) neonates were diagnosed with congenital anomalies; of which 120 (60.3%), 146 (73.4%), 144 (72.4%) and 30 (15.1%) of neonates were males, urban dwellers, delivered with normal birth weight and had multiple congenital anomalies, respectively. Central nervous system was the most commonly affected body system 56 (28.1%), followed by the gastrointestinal tract 41 (20.1%) and musculoskeletal system 32 (16.1%). The proportion of congenital anomalies was significantly increasing over time.

CONCLUSION

The overall prevalence of congenital anomalies was high and increased from year to year. The proportions observed in the study indicated that a significant number of neonates were affected and suffered from the impacts of congenital anomalies which need immediate preventive actions such as iron folate supplementation during preconception and early pregnancy. Therefore, design strategies to create community awareness and prevention mechanism of congenital anomalies, and strengthening the care and rehabilitation services for affected patients are crucial.

摘要

引言

先天性异常是一个重大的公共卫生问题,其定义为在子宫内生活期间发生的结构或功能异常,这些异常可在产前、出生时被检测到,有时可能仅在婴儿期后期才被发现。与其他发达国家和发展中国家相比,先天性异常在中低收入国家的影响更为严重。

目的

评估2017年至2019年在吉马医疗中心住院的新生儿中先天性异常的患病率及趋势。

方法

对2017 - 2019年在吉马医疗中心住院的新生儿进行基于机构的回顾性描述性横断面研究。对变量进行描述性分析(频率和百分比)。结果以表格、文本和图表形式呈现。

结果

在总共3346名住院新生儿中,199名(5.95%)新生儿被诊断患有先天性异常;其中分别有120名(60.3%)、146名(73.4%)、144名(72.4%)和30名(15.1%)新生儿为男性、城市居民、出生体重正常以及患有多种先天性异常。中枢神经系统是最常受影响的身体系统,有56例(28.1%),其次是胃肠道41例(20.1%)和肌肉骨骼系统32例(16.1%)。先天性异常的比例随时间显著增加。

结论

先天性异常的总体患病率较高且逐年上升。研究中观察到的比例表明,大量新生儿受到先天性异常的影响并遭受其后果,这需要立即采取预防措施,如在孕前和孕早期补充铁和叶酸。因此,制定提高社区对先天性异常的认识和预防机制的策略,以及加强对受影响患者的护理和康复服务至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92e1/7898197/05069d2e7285/PHMT-12-61-g0001.jpg

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