2型糖尿病患者的皮肤变化及其对生活质量的影响。

Skin Changes in Patients with Diabetes Melitus Type 2 and their Impact on Quality of Life.

作者信息

Kurtalic Nermina, Kurtalic Sadat, Salihbegovic Eldina Malkic

机构信息

Cantonal Hospital "Dr Irfan Ljubijankic" Bihac, Bosnia and Herzegovina.

Health Medical Center, Zivinice, Bosnia and Herzegovina.

出版信息

Mater Sociomed. 2020 Dec;32(4):283-286. doi: 10.5455/msm.2020.32.283-286.

DOI:10.5455/msm.2020.32.283-286

PMID:33628131

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7879440/

Abstract

INTRODUCTION

Changes in the skin can occur as part of a diabetic, metabolic disorder or diabetic complications. Studies have shown that diabetes has an extremely strong negative impact on quality of life, especially diabetes with complications.

AIM

Examine the impact of skin changes in patients with type 2 diabetes mellitus on quality of life.

METHODS

A prospective study analysed the quality of life in 200 respondents with type 2 diabetes mellitus which had diabetes-related skin changes. Subjects were divided into four groups according to the type of skin changes associated with diabetes mellitus. Group 1 consisted of patients which had skin changes with a greater or lesser association with diabetes mellitus, group 2 patients with infections, group 3 patients with cutaneous manifestations of diabetic complications and group 4 patients with allergic reactions to antidiabetic therapy. Quality of life assessment was performed using the Skindex-29 questionnaire, and the Nijsten categorization was used to assess the impact of skin changes in patients with type 2 diabetes mellitus on quality of life.

RESULTS

There were (51.95%) respondents in group 1, group 2 (24.02%), group 3 (22.22%) and group 4 (1.8%) respondents. In the scale of emotions in 84 respondents (43.0%) the impact on quality of life was serious, in the scale of symptoms in 96 (48%) was moderate, and in the scale of social and physical functioning 106 (55%) also had a moderate impact on quality of life, as well as in the total score of 94 respondents (47%). There was a statistically significant difference in the scale of social and physical functioning in the presence of skin changes in group 1 (x2 = 7.95; df = 3, p = 0.045) and group 3 (x2 = 12.48, df = 3; p = 0.006), and in the total score of Skindex-29 when it comes to changes in the skin of group 3 (x2 = 7.26, df = 3, p = 0.05).

CONCLUSION

the quality of life in patients with type 2 diabetes mellitus which have skin changes is significantly reduced.

摘要

引言

皮肤变化可能是糖尿病、代谢紊乱或糖尿病并发症的一部分。研究表明，糖尿病对生活质量有极其严重的负面影响，尤其是伴有并发症的糖尿病。

目的

研究2型糖尿病患者皮肤变化对生活质量的影响。

方法

一项前瞻性研究分析了200名患有与糖尿病相关皮肤变化的2型糖尿病患者的生活质量。根据与糖尿病相关的皮肤变化类型，将受试者分为四组。第1组由与糖尿病有或多或少关联的皮肤变化患者组成，第2组为感染患者，第3组为糖尿病并发症皮肤表现患者，第4组为对抗糖尿病治疗过敏反应的患者。使用Skindex - 29问卷进行生活质量评估，并采用奈斯滕分类法评估2型糖尿病患者皮肤变化对生活质量的影响。

结果

第1组有（51.95%）的受访者，第2组（24.02%），第3组（22.22%）和第4组（1.8%）的受访者。在84名受访者（43.0%）的情绪量表中，对生活质量的影响严重，在96名受访者（48%）的症状量表中影响为中度，在106名受访者（55%）的社会和身体功能量表中对生活质量也有中度影响，在94名受访者（47%）的总分中也是如此。在第1组（x2 = 7.95；自由度 = 3，p = 0.045）和第3组（x2 = 12.48，自由度 = 3；p = 0.006）存在皮肤变化时，社会和身体功能量表存在统计学显著差异，在涉及第3组皮肤变化时Skindex - 29总分也存在差异（x2 = 7.26，自由度 = 3，p = 0.05）。