Balakrishnan V, Sauniere J F, Hariharan M, Sarles H
Department of Gastroenterology, Medical College, Trivandrum, Kerala, India.
Pancreas. 1988;3(1):30-5. doi: 10.1097/00006676-198802000-00006.
The usual consumption of calories, fat, protein, and carbohydrate, and the exocrine pancreatic function estimated in duodenal juice after an intravenous injection of secretin and cholecystokinin (CCK), have been studied with the same method and by the same team in Kerala (South India) and in Marseille (France) in apparently normal children (7 Indians, 21 French), in normal adults (23 Indians, 17 French), and in patients presenting with chronic calcifying pancreatitis (8 Indian children, 28 Indian adults, 25 French adults). Although they had a low protein intake (children controls: 32.1 +/- 14 g/day (SM), children pancreatitis: 51.1 +/- 15, adult controls: 51.3 +/- 4.9, adult pancreatitis: 55.7 +/- 5.7), the exocrine secretion of Indian controls was not very much modified in comparison with Europeans. Therefore, Indians are less affected by the insufficient diet than the population of Ivory Coast previously studied by the same group. The diet of Indian patients is characterized by a moderately low protein intake and a very low fat intake (18.5 g/day +/- 2.3 (SM) for children 23.4 g/day + 2.7 for adult patients). Comparison between different series of patients studied in different countries with the same method suggests that kwashiorkor or cassava consumption have no evident role in the etiology of chronic tropical pancreatitis. The possible role of a low fat diet is suggested and needs further exploration.
在喀拉拉邦（印度南部）和马赛（法国），同一研究团队采用相同方法，对明显正常的儿童（7名印度儿童、21名法国儿童）、正常成年人（23名印度成年人、17名法国成年人）以及患有慢性钙化性胰腺炎的患者（8名印度儿童、28名印度成年人、25名法国成年人），研究了卡路里、脂肪、蛋白质和碳水化合物的日常摄入量，以及静脉注射促胰液素和胆囊收缩素（CCK）后十二指肠液中估计的胰腺外分泌功能。尽管他们的蛋白质摄入量较低（儿童对照组：32.1±14克/天（标准误），儿童胰腺炎患者：51.1±15，成人对照组：51.3±4.9，成人胰腺炎患者：55.7±5.7），但与欧洲人相比，印度对照组的外分泌功能变化不大。因此，与该研究团队之前研究的象牙海岸人群相比，印度人受饮食不足的影响较小。印度患者的饮食特点是蛋白质摄入量适度偏低，脂肪摄入量非常低（儿童为18.5克/天±2.3（标准误），成年患者为23.4克/天+2.7）。用相同方法对不同国家的不同患者系列进行比较表明，夸休可尔症或木薯食用量在慢性热带胰腺炎的病因中没有明显作用。研究提示低脂饮食可能起作用，这需要进一步探究。
