Laugier R, Bernard J P, Laroche R, Kadende P, N'Dabaneze E, Saunière J F, Dupuy P
INSERM U 260, Faculté de Médecine, Unité de Recherche de Physiopathologie des Régulations hormono-nutritionnelles, Marseille, France.
Digestion. 1993;54(1):54-60. doi: 10.1159/000201012.
Pure pancreatic juice composition was studied, after secretin and cerulein stimulation in 29 people from Burundi (Central Africa): 17 controls and 12 alcoholic chronic pancreatitis (CP) patients. Results were compared to similar data in France. African controls had a similar pancreatic response to hormones apart from a much lower lipase secretion than French controls. In the early non-calcified stage of African CP water and bicarbonate secretion were markedly diminished while protein and lipase concentrations were enhanced. In the late stage, secretion was exhausted except that of calcium. Nutritional data were obtained under the same conditions in 40 African controls and in 34 CP patients (including all patients tested for secretion). African controls had a very low fat intake (35.2 +/- 2.6 g/day), and patients had a higher protein and fat intake (144.7 +/- 5.9 and 66.2 +/- 4.8 g/day, respectively) than local controls: as in other countries, CP was associated with a diet enriched in alcohol, fat and protein.
对来自布隆迪（中非）的29人（17名对照者和12名酒精性慢性胰腺炎（CP）患者）进行促胰液素和雨蛙肽刺激后，研究了纯胰液成分。将结果与法国的类似数据进行了比较。非洲对照者对激素的胰腺反应相似，但脂肪酶分泌比法国对照者低得多。在非洲CP的早期非钙化阶段，水和碳酸氢盐分泌明显减少，而蛋白质和脂肪酶浓度增加。在晚期，除钙分泌外，其他分泌均耗尽。在相同条件下，获取了40名非洲对照者和34名CP患者（包括所有接受分泌测试的患者）的营养数据。非洲对照者的脂肪摄入量非常低（35.2±2.6克/天），患者的蛋白质和脂肪摄入量（分别为144.7±5.9克/天和66.2±4.8克/天）高于当地对照者：与其他国家一样，CP与富含酒精、脂肪和蛋白质的饮食有关。
