Zabihi-Pour Dorsa, Bahrani Bahar, Assaad Dalal, Yeung Jensen
Schulich School of Medicine & Dentistry, London, ON, Canada.
Division of Dermatology, Department of Medicine, University of Toronto, Women's College Hospital, Toronto, ON, Canada.
SAGE Open Med Case Rep. 2021 Feb 11;9:2050313X20979560. doi: 10.1177/2050313X20979560. eCollection 2021.
Palisaded neutrophilic granulomatous dermatitis is a rare inflammatory dermatosis with possible underlying systemic conditions including rheumatoid arthritis, autoimmune connective tissue disease, and malignancies.
We report a case of an 84-year-old man presenting with a 3-week eruption of asymptomatic annular plaques on his neck, which progressed to involve his back and legs. Skin biopsies confirmed a diagnosis of palisaded neutrophilic granulomatous dermatitis, and he was treated with prednisone. Full workup related to potential underlying causes of palisaded neutrophilic granulomatous dermatitis was completed.
Palisaded neutrophilic granulomatous dermatitis may precede the onset of underlying systemic conditions or occur concomitantly. Following the diagnosis, clinicians should perform a comprehensive focused history, physical examination, and laboratory investigation related to the associated underlying diseases.
栅栏状中性粒细胞肉芽肿性皮炎是一种罕见的炎症性皮肤病，可能伴有潜在的全身性疾病，包括类风湿性关节炎、自身免疫性结缔组织病和恶性肿瘤。
我们报告一例84岁男性患者，其颈部出现无症状环形斑块3周，皮疹进展至背部和腿部。皮肤活检确诊为栅栏状中性粒细胞肉芽肿性皮炎，患者接受泼尼松治疗。完成了与栅栏状中性粒细胞肉芽肿性皮炎潜在病因相关的全面检查。
栅栏状中性粒细胞肉芽肿性皮炎可能先于潜在全身性疾病出现或与之同时发生。诊断后，临床医生应针对相关潜在疾病进行全面、有重点的病史询问、体格检查和实验室检查。
