Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.
College of Dentistry, Ajman University, Ajman, UAE.
Biomed Res Int. 2021 Feb 12;2021:6652250. doi: 10.1155/2021/6652250. eCollection 2021.
To evaluate the effectiveness of desensitizing agents in reducing dentine permeability.
The efficacy of desensitizing agents in reducing dentine permeability by occluding dentine tubules was evaluated using a fluid filtration device that conducts at 100 cmHO (1.4 psi) pressure, and SEM/EDX analyses were evaluated and compared. Forty-two dentine discs ( = 42) of 1 ± 0.2 mm width were obtained from caries-free permanent human molars. Thirty dentine discs ( = 30) were randomly divided into 3 groups ( = 10): Group 1: 2.7% wt. monopotassium-monohydrogen oxalate (Mp-Mh oxalate), Group 2: RMGI XT VAR, and Group 3: LIQ SiO. Dentine permeability was measured following treatment application after 10 minutes, storage in artificial saliva after 10 minutes and 7 days, and citric acid challenge for 3 minutes. Data were analysed with a repeated measures ANOVA test. Dentine discs ( = 12) were used for SEM/EDX analyses to acquire data on morphological changes on dentine surface and its mineral content after different stages of treatment.
Desensitizing agents' application on the demineralized dentine discs exhibited significant reduction of permeability compared to its maximum acid permeability values. Mp-Mh oxalate showed a significant reduction in dentine permeability ( < 0.05) when compared to RMGI XT VAR and LIQ SiO. On SEM/EDX analysis, all the agents formed mineral precipitates that occluded the dentine tubules.
2.7% wt. monopotassium-monohydrogen oxalate was significantly effective in reducing dentine permeability compared to RMGI XT VAR and LIQ SiO.
评估脱敏剂降低牙本质渗透性的效果。
使用在 100cmHO（1.4psi）压力下运行的流体过滤装置评估脱敏剂通过阻塞牙本质小管来降低牙本质渗透性的效果，并进行 SEM/EDX 分析和比较。从无龋恒磨牙中获得 42 个（=42）宽度为 1±0.2mm 的牙本质圆盘。30 个牙本质圆盘（=30）随机分为 3 组（=10）：组 1：2.7%wt.单钾单氢草酸盐（Mp-Mh 草酸盐），组 2：RMGI XT VAR，组 3：LIQ SiO。处理应用后 10 分钟、10 分钟和 7 天后储存在人工唾液中以及柠檬酸挑战 3 分钟后测量牙本质渗透性。使用重复测量方差分析检验分析数据。使用 SEM/EDX 分析 12 个牙本质圆盘，以获取不同治疗阶段后牙本质表面形态变化及其矿物质含量的数据。
与最大酸渗透性值相比，脱敏剂应用于脱矿牙本质圆盘可显著降低渗透性。与 RMGI XT VAR 和 LIQ SiO 相比，Mp-Mh 草酸盐显著降低牙本质渗透性（<0.05）。在 SEM/EDX 分析中，所有试剂都形成了矿化沉淀物，阻塞了牙本质小管。
与 RMGI XT VAR 和 LIQ SiO 相比，2.7%wt.单钾单氢草酸盐在降低牙本质渗透性方面效果显著。
