Biomaterials, Biometrics & Biophotonics, King's College London Dental Institute, Guy's, King's College and St Thomas' Hospitals, London, United Kingdom.
Oper Dent. 2011 Mar-Apr;36(2):222-30. doi: 10.2341/10-225-L.
The aim of this study was to evaluate the dentin remineralization induced by bioactive substances contained in common dental materials used in preventive and operative dentistry. Several materials were applied on human dentin segments. Dentin permeability was quantified using a fluid filtration system working at 20 cm H(2)O. Micro-Raman, SEM-EDX, and microhardness calculation were used to evaluate changes in the mineralization of dentin. Dentin treated with the prophylactic materials showed different dentin permeability values, in particular subsequent to immersion in remineralizing solutions (RSS). The bioactive glass (Sylc) was the only substance able to reduce dentin permeability after immersion in remineralizing solution and to show hydroxyapatite precipitation as a sign of dentin remineralization. The reduction in dentin permeability obtained after the application of the other prophylactic materials used in this study was due to the presence of the remnant material in the dentinal tubules, with no remineralization effect after storage in remineralizing solution. In conclusion, the results indicated that bioactive glass prophy powder may induce immediate remineralization of dentin.
本研究旨在评估在预防性和手术性牙科中常用的牙科材料中所含的生物活性物质对牙本质再矿化的诱导作用。将几种材料应用于人牙本质段。使用在 20 cm H(2)O 下工作的流体过滤系统来量化牙本质渗透性。使用微拉曼、SEM-EDX 和显微硬度计算来评估牙本质矿化的变化。用预防性材料处理的牙本质显示出不同的牙本质渗透性值,特别是在浸入再矿化溶液(RSS)后。生物活性玻璃(Sylc)是唯一能在浸入再矿化溶液后降低牙本质渗透性并显示出羟基磷灰石沉淀作为牙本质再矿化迹象的物质。在这项研究中使用的其他预防性材料应用后获得的牙本质渗透性降低是由于牙本质小管中存在残余材料,在再矿化溶液中储存后没有再矿化效果。总之,结果表明,生物活性玻璃预涂粉可能会立即诱导牙本质再矿化。