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本文引用的文献

1
Omadacycline for the Treatment of Disease: A Case Series.奥马环素治疗疾病:病例系列
Open Forum Infect Dis. 2020 Sep 9;7(10):ofaa415. doi: 10.1093/ofid/ofaa415. eCollection 2020 Oct.
2
Early Experience With Eravacycline for Complicated Infections.依拉环素用于复杂感染的早期经验
Open Forum Infect Dis. 2020 Mar 2;7(5):ofaa071. doi: 10.1093/ofid/ofaa071. eCollection 2020 May.
3
Omadacycline: A Modernized Tetracycline.奥马环素:一种现代化的四环素类药物。
Clin Infect Dis. 2019 Aug 1;69(Suppl 1):S1-S5. doi: 10.1093/cid/ciz394.
4
Activity of New Tetracycline Analogs Omadacycline and Eravacycline against Drug-Resistant Clinical Isolates of .新型四环素类似物奥马环素和依拉环素对.耐药临床分离株的活性
Antimicrob Agents Chemother. 2019 May 24;63(6). doi: 10.1128/AAC.00470-19. Print 2019 Jun.
5
Activities of Omadacycline against Rapidly Growing Mycobacteria.奥马环素对快速生长分枝杆菌的活性。
Antimicrob Agents Chemother. 2019 Apr 25;63(5). doi: 10.1128/AAC.02522-18. Print 2019 May.
6
Omadacycline for Community-Acquired Bacterial Pneumonia.奥马环素治疗社区获得性细菌性肺炎。
N Engl J Med. 2019 Feb 7;380(6):517-527. doi: 10.1056/NEJMoa1800201.
7
Complex Infections: A Retrospective Cohort Study.复杂感染:一项回顾性队列研究
Open Forum Infect Dis. 2018 Feb 9;5(2):ofy022. doi: 10.1093/ofid/ofy022. eCollection 2018 Feb.
8
Treatment of Non-Tuberculous Mycobacterial Lung Disease.非结核分枝杆菌肺病的治疗
Curr Treat Options Infect Dis. 2016 Dec;8(4):275-296. doi: 10.1007/s40506-016-0086-4. Epub 2016 Oct 11.
9
Patient-Centered Research Priorities for Pulmonary Nontuberculous Mycobacteria (NTM) Infection. An NTM Research Consortium Workshop Report.非结核分枝杆菌(NTM)肺部感染以患者为中心的研究重点。一份NTM研究联盟研讨会报告。
Ann Am Thorac Soc. 2016 Sep;13(9):S379-84. doi: 10.1513/AnnalsATS.201605-387WS.
10
Inducible and Acquired Clarithromycin Resistance in the Mycobacterium abscessus Complex.脓肿分枝杆菌复合群中的诱导性和获得性克拉霉素耐药性
PLoS One. 2015 Oct 8;10(10):e0140166. doi: 10.1371/journal.pone.0140166. eCollection 2015.

奥马环素治疗感染的初步、真实世界、多中心经验

Preliminary, Real-world, Multicenter Experience With Omadacycline for Infections.

作者信息

Morrisette Taylor, Alosaimy Sara, Philley Julie V, Wadle Carly, Howard Catessa, Webb Andrew J, Veve Michael P, Barger Melissa L, Bouchard Jeannette, Gore Tristan W, Lagnf Abdalhamid M, Ansari Iman, Mejia-Chew Carlos, Cohen Keira A, Rybak Michael J

机构信息

Anti-Infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan, USA.

Division of Pulmonary and Critical Care Medicine, University of Texas Health Science Center, University of Texas, Tyler, Texas, USA.

出版信息

Open Forum Infect Dis. 2021 Jan 7;8(2):ofab002. doi: 10.1093/ofid/ofab002. eCollection 2021 Feb.

DOI:10.1093/ofid/ofab002
PMID:33628856
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7890947/
Abstract

Twelve patients were treated with omadacycline (OMC) as part of a multidrug regimen for . The majority of infections were of pulmonary origin (7/12; 58.3%). The median (interquartile range) duration of OMC was 6.2 (4.2-11.0) months. Clinical success occurred in 9/12 (75.0%) patients. Three patients experienced a possible adverse effect while on therapy.

摘要

12名患者接受了奥马环素(OMC)治疗,作为多药治疗方案的一部分用于……。大多数感染起源于肺部(7/12;58.3%)。奥马环素治疗的中位(四分位间距)持续时间为6.2(4.2 - 11.0)个月。9/12(75.0%)的患者临床治疗成功。3名患者在治疗期间出现了可能的不良反应。