Yang Chao, Wang Wei-Feng, Du Xiao-Juan, Tan Xiao, Suo Li-Juan, Bian Kun, Li Fei-Ran, Tang Jie, Jiang Ben-Mo, Li Xue-Juan, Wang Yan
Shaanxi Institute of Zoology, Xi'an, PR China.
School of Life Sciences, Shaanxi Normal University, Xi'an, PR China.
Mitochondrial DNA B Resour. 2021 Feb 13;6(2):598-600. doi: 10.1080/23802359.2021.1875930.
Alpine musk deer, , a solitary, primitive ungulate inhabiting high elevation areas (3000-4500 m) is an endangered species facing threat of extinction globally due to excessive hunting for its musk. In this study, we determined the complete mitochondrial genome of , which was 16,354 bp in length, and revealed the same gene order and genomic organization as typical Moschidae mitochondrial DNA. Start codons in 13 protein-coding genes (PCGs) were all typical ATGs except ATA for and and ATT for . Stop codons were all typical types except an incomplete stop codon T for , , , and . Secondary structures in 22 transfer RNA genes all showed typical cloverleaf except (AGY), in which the dihydrouridine arm formed a simple loop. No repeat units were found in the control region. The topology structure indicated that was primitive and located at the root of the Moschidae clade. Phylogenetic reconstruction placed as a distinct lineage, closely related to the branch of , (wild) and predicted a sister relationship with , and (captive). However, we suggested that the genetic resources of JQ608470 should be further investigated.
高山麝，一种独居的原始有蹄类动物，栖息于高海拔地区（3000 - 4500米），由于其麝香遭到过度捕猎，已成为全球面临灭绝威胁的濒危物种。在本研究中，我们测定了高山麝的完整线粒体基因组，其长度为16354 bp，并揭示了与典型麝科线粒体DNA相同的基因顺序和基因组结构。13个蛋白质编码基因（PCGs）的起始密码子除了 和 的ATA以及 的ATT外均为典型的ATG。终止密码子除了 、 、 和 的不完全终止密码子T外均为典型类型。22个转运RNA基因的二级结构除了 （AGY）形成简单环的二氢尿嘧啶臂外均显示典型的三叶草结构。在控制区未发现重复单元。拓扑结构表明高山麝较为原始，位于麝科进化枝的根部。系统发育重建将高山麝置于一个独特的谱系中，与 、 （野生）的分支密切相关，并预测与 、 和 （圈养）为姐妹关系。然而，我们建议应进一步研究JQ608470的遗传资源。
