Tianjin Key Laboratory of Imaging and Sensing Microelectronic Technology, School of Microelectronics, Tianjin University, Tianjin, People's Republic of China.
Research Institute for Nanodevice and Bio Systems, Hiroshima University, Higashi-Hiroshima, Japan.
Med Biol Eng Comput. 2021 Mar;59(3):721-731. doi: 10.1007/s11517-021-02339-5. Epub 2021 Feb 24.
The accurate detection of early breast cancer is of great significance to each patient. In recent years, breast cancer non-invasive detection technology based on Ultra-Wideband (UWB) microwave has been proposed and developed extensively, which is complementary to the existing methods. In this paper, a novel approach is proposed for tumor existence detection based on feature extraction algorithm. Firstly, the breast features are obtained by Ensemble Empirical Mode Decomposition (EEMD) and valid correlation Intrinsic Mode Function (IMF) selection. Secondly, raw feature datasets are constructed and then simplified by Principal Component Analysis (PCA) or Recursive Feature Elimination (RFE). Finally, the detection is realized by Support Vector Machines (SVM). The influence of different kernel functions and feature selection methods on detection results is compared. In this study, 11,232 sets of backscatter signals from simulation results of four different categories' breast models are utilized. And feature dataset is constructed by 24 specific features from each signal's four valid components. The results demonstrate that the proposed method can extract representative features and detect the early breast cancer effectively with the accuracy of 84.8%.
准确检测早期乳腺癌对每位患者都具有重要意义。近年来,基于超宽带(UWB)微波的乳腺癌非侵入性检测技术得到了广泛的提出和发展,它与现有的方法互为补充。在本文中,我们提出了一种基于特征提取算法的肿瘤存在检测的新方法。首先,通过集合经验模态分解(EEMD)和有效相关固有模态函数(IMF)选择获取乳房特征。其次,构建原始特征数据集,并通过主成分分析(PCA)或递归特征消除(RFE)进行简化。最后,通过支持向量机(SVM)实现检测。比较了不同核函数和特征选择方法对检测结果的影响。在本研究中,利用四个不同类别的乳房模型的模拟结果中的 11232 组反向散射信号,从每个信号的四个有效分量中的每个信号构建特征数据集。结果表明,该方法可以提取有代表性的特征,并以 84.8%的准确率有效地检测早期乳腺癌。