Balon R, Pohl R, Yeragani V K, Rainey J M, Weinberg P
Lafayette Clinic, Detroit, MI 48207.
Psychiatry Res. 1988 Feb;23(2):153-60. doi: 10.1016/0165-1781(88)90005-4.
In a double-blind study using sodium lactate and isoproterenol infusions to provoke panic attacks, 73 of 86 panic disorder patients and 10 of 45 controls panicked with lactate, and 58 of 86 patients and 4 of 45 controls panicked with isoproterenol. We measured baseline and peak anxiety ratings in 10 controls with lactate-induced panic attacks, 31 controls who did not panic during lactate infusions, and 63 panic disorder patients who did panic during lactate infusions. The controls who panicked with lactate had robust increases in their anxiety ratings very similar to the increases experienced by patients who panicked with lactate.
在一项使用输注乳酸钠和异丙肾上腺素诱发惊恐发作的双盲研究中，86名惊恐障碍患者中有73名、45名对照组中有10名在输注乳酸时出现惊恐发作；86名患者中有58名、45名对照组中有4名在输注异丙肾上腺素时出现惊恐发作。我们对10名在输注乳酸时出现惊恐发作的对照组、31名在输注乳酸期间未出现惊恐发作的对照组以及63名在输注乳酸期间出现惊恐发作的惊恐障碍患者，测量了其基线焦虑评分和峰值焦虑评分。在输注乳酸时出现惊恐发作的对照组，其焦虑评分大幅增加，与在输注乳酸时出现惊恐发作的患者所经历的增加情况非常相似。
