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[处于生长静止期的海拉肿瘤细胞群体对不同照射速率的反应]

[Reaction of a population of HeLa tumor cells in the stationary stage of growth to irradiation at different rates].

作者信息

Semeniak O Iu, Kalendo G S, Serebriakov N G

出版信息

Radiobiologiia. 1988 Mar-Apr;28(2):178-83.

PMID:3363092
Abstract

The early stages of a repopulation process of HeLa cells under the action of irradiation 5 Gy dose and an influence of a preliminary 0.1 Gy dose irradiation at that process were investigated. As it was shown the fraction of cells with a great proliferation potential appeared in one day after lethal 5 Gy dose irradiation of the resting HeLa cells. If the other irradiation regime was used: 0.1 Gy dose plus 4.9 Gy dose in 3 min after the first action, the part of cells with a great proliferation potential became considerably less.

摘要

研究了在5 Gy剂量辐照作用下以及在此过程中预先0.1 Gy剂量辐照的影响下HeLa细胞再增殖过程的早期阶段。结果表明,静止的HeLa细胞经致死性5 Gy剂量辐照一天后出现具有高增殖潜力的细胞部分。如果采用另一种辐照方案:0.1 Gy剂量加第一次照射后3分钟的4.9 Gy剂量,则具有高增殖潜力的细胞部分会显著减少。

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