Center for Health Decision Science, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Hum Vaccin Immunother. 2021 Aug 3;17(8):2630-2638. doi: 10.1080/21645515.2021.1880860. Epub 2021 Feb 25.
: Vaccination coverage among undernourished children often associated with higher risk of contracting infectious diseases due to lowered immunity is a critical public health concern. The vaccination coverage is low and the child mortality rate is high in Nigeria. This study investigates the association between selected vaccines uptake and undernutrition among Nigerian children.: The 2018 Nigeria Demographic and Health Survey dataset was used for this study. Children aged 0-36 months were included in the study. Stunting and wasting were the main outcome variables to define undernutrition outcomes. The effect of BCG, first dose of DPT/Pentavalent (DPT/Penta1), third dose of DPT/Pentavalent (DPT/Penta3) and measles vaccines on nutrition outcomes were individually examined using logistic regression at 5% significance level.: Among 6,928 children aged 0 to 36 months old, 34.4% were stunted and 8.7% were wasted, while the vaccination rate was 70.0% (BCG), 65.0% (DPT/Penta1), 48.2% (DPT/Penta1), and 43.6% (measles). Vaccination uptake was consistently associated with less likelihood of stunting, while it was not associated with wasting. We also found that some vaccination uptake was negatively associated with stunting particularly among older children.: The finding that vaccination is associated with less likelihood of stunting implies that the vaccination can be important to enhance the long-term nutrition outcomes. Targeting children with disadvantageous sociodemographic characteristics for vaccination can further enhance the overall nutrition outcomes among them.
: 营养不良儿童的疫苗接种率往往较低,由于免疫力下降,他们更容易感染传染病,这是一个严重的公共卫生问题。尼日利亚的疫苗接种率低,儿童死亡率高。本研究调查了尼日利亚儿童中某些疫苗接种率与营养不良之间的关联。: 本研究使用了 2018 年尼日利亚人口与健康调查数据集。研究纳入了 0-36 个月龄的儿童。发育迟缓症和消瘦症是定义营养不良结局的主要结果变量。使用逻辑回归,在 5%的显著性水平下,分别检查了卡介苗、第一剂白喉-破伤风-百日咳/五联疫苗(DTaP/Penta1)、第三剂白喉-破伤风-百日咳/五联疫苗(DTaP/Penta3)和麻疹疫苗对营养结局的影响。: 在 6928 名 0 至 36 个月大的儿童中,34.4%发育迟缓,8.7%消瘦,而疫苗接种率为 70.0%(卡介苗)、65.0%(DTaP/Penta1)、48.2%(DTaP/Penta1)和 43.6%(麻疹)。疫苗接种率与发育迟缓的可能性降低有关,而与消瘦无关。我们还发现,一些疫苗接种率与发育迟缓呈负相关,特别是在年龄较大的儿童中。: 疫苗接种与发育迟缓的可能性降低有关的发现意味着疫苗接种对增强长期营养结局很重要。针对具有不利社会人口特征的儿童进行疫苗接种,可以进一步提高他们的整体营养结局。