The Laboratory for Molecular Infection Medicine Sweden (MIMS), Department of Molecular Biology, Umeå University, 90187 Umeå, Sweden.
The Laboratory for Molecular Infection Medicine Sweden (MIMS), Department of Molecular Biology, Umeå University, 90187 Umeå, Sweden.
Curr Opin Microbiol. 2021 Apr;60:88-95. doi: 10.1016/j.mib.2021.01.010. Epub 2021 Feb 22.
Peptidoglycan (PG) has remained for decades in the spotlight of the never-ending battle against pathogenic bacteria as this essential bacterial structure is one of the most successful targets for antibiotics. Most of our current understanding about the composition, architecture, and dynamics of the PG relies on techniques which have experienced great technological and methodological improvements in the past years. Here we summarize recent advances in these methods with the intention to furnish a valuable resource for both PG experts and newcomers.
肽聚糖 (PG) 作为抗生素最成功的靶点之一，几十年来一直是对抗致病菌的永无止境的战斗焦点。我们目前对 PG 的组成、结构和动态的大部分了解都依赖于过去几年中经历了重大技术和方法改进的技术。在这里，我们总结了这些方法的最新进展，旨在为 PG 专家和新手提供有价值的资源。
