Department of Neurologic Sciences, Rush University, Chicago, IL, United States.
Handb Clin Neurol. 2021;177:163-174. doi: 10.1016/B978-0-12-819814-8.00006-8.
Brady-arrhythmias are responsible for both overt as well as subtle neurologic signs and symptoms, from the seemingly benign and nonspecific symptoms associated with presyncope, to sudden focal neurologic deficits. A brief background on nodal and infra-nodal brady-arrhythmias is provided, followed by extensive discussion regarding neurologic complications of brady-arrhythmias. The multiple mechanisms of and associations between Brady-arrhythmias and transient ischemic attacks and ischemic stroke are discussed. Controversial associations between brady-arrhythmias and neurologic disease are discussed as well, such as potential roles of brady-arrhythmias in cognitive impairment and sequelae of chronotropic incompetence; and the contribution of brady-arrhythmias to syncope and associated injuries to the nervous system. The chapter is written to stand on its own, with guidance toward other pertinent sections of this text where appropriate for further reading.
缓心律失常可导致明显和隐匿的神经系统体征和症状，从与晕厥前相关的看似良性和非特异性症状，到突发局灶性神经功能缺损。简要介绍了结性和结下性缓心律失常的背景，随后广泛讨论了缓心律失常的神经系统并发症。文中讨论了缓心律失常与短暂性脑缺血发作和缺血性脑卒中之间的多种机制和关联。文中还讨论了缓心律失常与神经疾病之间存在争议的关联，例如缓心律失常在认知障碍和变时性功能不全后遗症中的潜在作用；以及缓心律失常对晕厥和相关神经系统损伤的影响。本章内容独立成篇，文中适当提供了指向本文本其他相关章节的指导，以供进一步阅读。
