From the Infection Prevention and Control Department (Farahat), King Abdulaziz Medical City, Ministry of National Guard Health Affairs; from King Abdullah International Medical Research Center (Farahat, Al-Jifree); from the College of Medicine (Farahat, Alshaikh, Al-Jifree), King Saud bin Abdulaziz University for Health Sciences, Jeddah; from the College of Medicine (Faqih), Umm Al-Qura University, Makkah; from the College of Medicine (Alharbi, Mudarris), Ibn Sina National College; and from the Department of Oncology (Al-Jifree), King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Kingdom of Saudi Arabia.
Saudi Med J. 2021 Mar;42(3):338-341. doi: 10.15537/smj.2021.42.3.20200603.
To investigate the epidemiological characteristics of cervical cancer cases reported at a tertiary care teaching hospital in western Saudi Arabia.
A retrospective chart review was conducted on medical records of patients diagnosed with cervical cancer at King Abdulaziz Medical City, Jeddah, Saudi Arabia. Data were collected on demographic characteristics, histological types and stage, treatment modalities, and disease outcomes.
Cervical cancer was diagnosed among 89 patients from 2002 to 2018. History of pap smear was reported among 31 cases (34.8%). Squamous cell carcinoma was the most common reported histopathological subtype. Almost one third (29.2%) of the patients were at stage III or IV at the time of diagnosis. The most frequent treatment regimen was combined radio/chemotherapy. Kaplan-Meier analysis showed an overall survival rate of 81.5%.
The lack of an effective screening program for cervical cancer increases the likelihood of a late diagnosis and higher rates of complications and mortality. Public health programs should focus on cancer screening, screening, and reporting HPV infections, and supporting HPV vaccination activities.
调查沙特阿拉伯西部一家三级保健教学医院报告的宫颈癌病例的流行病学特征。
对沙特阿拉伯吉达阿卜杜勒阿齐兹国王医疗城诊断为宫颈癌的患者的病历进行回顾性图表审查。收集人口统计学特征、组织学类型和分期、治疗方式和疾病结局等数据。
2002 年至 2018 年期间,共诊断出 89 例宫颈癌患者。有 31 例(34.8%)报告有巴氏涂片检查史。鳞状细胞癌是最常见的报告组织病理学亚型。近三分之一(29.2%)的患者在诊断时处于 III 期或 IV 期。最常见的治疗方案是联合放化疗。Kaplan-Meier 分析显示总生存率为 81.5%。
缺乏有效的宫颈癌筛查计划增加了晚期诊断和更高并发症和死亡率的可能性。公共卫生计划应侧重于癌症筛查、HPV 感染的筛查和报告,以及支持 HPV 疫苗接种活动。