Deyrup Stephen T, Stagnitti Natalie C, Perpetua Mackenzie J, Wong-Deyrup Siu Wah
Department of Chemistry and Biochemistry, Siena College, Loudonville, NY 12309, USA.
The RNA Institute and Department of Biological Sciences, University at Albany, State University of New York, Albany, NY 12222, USA.
Biomol Ther (Seoul). 2021 Mar 1;29(2):105-126. doi: 10.4062/biomolther.2020.229.
Traditional Chinese medicine (TCM) was the primary source of medical treatment for the people inhabiting East Asia for thousands of years. These ancient practices have incorporated a wide variety of materia medica including plants, animals and minerals. As modern sciences, including natural products chemistry, emerged, there became increasing efforts to explore the chemistry of this materia medica to find molecules responsible for their traditional use. Insects, including beetles have played an important role in TCM. In our survey of texts and review articles on TCM materia medica, we found 48 species of beetles from 34 genera in 14 different families that are used in TCM. This review covers the chemistry known from the beetles used in TCM, or in cases where a species used in these practices has not been chemically studied, we discuss the chemistry of closely related beetles. We also found several documented uses of beetles in Traditional Korean Medicine (TKM), and included them where appropriate. There are 129 chemical constituents of beetles discussed.
几千年来，传统中医一直是东亚居民的主要医疗来源。这些古老的疗法使用了各种各样的药材，包括植物、动物和矿物质。随着包括天然产物化学在内的现代科学的出现，人们越来越努力地探索这些药材的化学性质，以寻找具有传统用途的分子。昆虫，包括甲虫，在传统中医中发挥了重要作用。在我们对传统中医药材的文献和综述文章的调查中，我们发现14个不同科的34个属的48种甲虫被用于传统中医。这篇综述涵盖了传统中医中使用的甲虫的已知化学性质，或者在这些疗法中使用的物种尚未进行化学研究的情况下，我们讨论了亲缘关系密切的甲虫的化学性质。我们还发现了甲虫在传统韩医中的一些文献记载用途，并在适当的地方纳入了这些用途。本文讨论了甲虫的129种化学成分。
