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甲状腺功能亢进患者心血管表现的发生率。

Frequency of Cardiovascular Manifestation in Patients With Hyperthyroidism.

作者信息

Khurana Naresh Kumar, Kumar Suresh, Kumar Sameet, Kumar Pardeep, Rizwan Amber

机构信息

Cardiology, Central Park Medical College, Lahore, PAK.

Internal Medicine, Bolan University of Medical & Health Sciences, Quetta, PAK.

出版信息

Cureus. 2021 Jan 21;13(1):e12839. doi: 10.7759/cureus.12839.

Abstract

Introduction Cardiovascular manifestations are very common in hyperthyroidism. Various cardiovascular symptoms such as palpitations, exercise intolerance, dyspnea, angina, edema, and congestive heart failure are commonly reported in hyperthyroidism. In this study, we determine the frequency of cardiovascular signs, symptoms, and various conduction disorders associated with hyperthyroidism. Methodology This cross-sectional, observational study was conducted in the cardiology department of a tertiary care hospital in Pakistan in close association with the internal medicine department from August 2019 to December 2019. A total of 100 hyperthyroid patients confirmed based on thyroid stimulating hormone (TSH, also known as thyrotropin), free T (FT; thyroxine), and free T (FT; triiodothyronine) were enrolled in the study. Results The most common cardiovascular symptom in this study was palpitations identified in 72% of the participants, followed by breathlessness in 41% of the participants. The most common cardiovascular sign was a pulse rate of more than 100 beats per minute found in 72% of the participants. The most common abnormality in electrocardiogram (ECG) was sinus tachycardia in 39% of the participants, followed by atrial fibrillation in 22% of the participants. In echocardiography, 5% of the participants had systolic dysfunction. Conclusion In this study, cardiovascular signs, symptoms, ECG, and echo changes were very frequent in hyperthyroidism. Management of hyperthyroidism should include routine ECG and echo testing, and cardiologists should be involved in thorough cardiovascular examination.

摘要

引言

心血管表现在甲状腺功能亢进症中非常常见。甲状腺功能亢进症患者常出现各种心血管症状,如心悸、运动不耐受、呼吸困难、心绞痛、水肿和充血性心力衰竭。在本研究中,我们确定了与甲状腺功能亢进症相关的心血管体征、症状及各种传导障碍的发生率。

方法

本横断面观察性研究于2019年8月至2019年12月在巴基斯坦一家三级护理医院的心脏病科与内科密切合作开展。基于促甲状腺激素(TSH,也称为促甲状腺素)、游离T4(FT4;甲状腺素)和游离T3(FT3;三碘甲状腺原氨酸)确诊的100例甲状腺功能亢进症患者纳入本研究。

结果

本研究中最常见的心血管症状是心悸,72%的参与者出现该症状,其次是呼吸困难,41%的参与者出现该症状。最常见的心血管体征是每分钟脉搏率超过100次,72%的参与者出现该体征。心电图(ECG)最常见的异常是窦性心动过速,39%的参与者出现该异常,其次是心房颤动,22%的参与者出现该异常。在超声心动图检查中,5%的参与者存在收缩功能障碍。

结论

在本研究中,甲状腺功能亢进症患者的心血管体征、症状、心电图及超声心动图改变非常常见。甲状腺功能亢进症的管理应包括常规心电图和超声心动图检查,心脏病专家应参与全面的心血管检查。

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