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克罗恩病与初次全髋关节置换术后住院时间延长、并发症发生率和费用增加有关。

Crohn's Disease is Associated with Longer In-Hospital Lengths of Stay and Higher Rates of Complications and Costs after Primary Total Hip Arthroplasty.

机构信息

Maimonides Medical Center, Department of Orthopedic Surgery, Brooklyn, NY.

Northwell Health, Lenox Hill Hospital, Department of Orthopaedic Surgery, New York, NY; Cleveland Clinic Hospital, Department of Orthopaedic Surgery, Cleveland, OH.

出版信息

J Arthroplasty. 2021 Jun;36(6):2110-2115. doi: 10.1016/j.arth.2021.02.002. Epub 2021 Feb 6.

Abstract

BACKGROUND

As the incidence and prevalence of Crohn's disease continues to change worldwide, rates within North America have been increasing. The objective of this study was to evaluate whether patients who have Crohn's disease undergoing primary total hip arthroplasties have worse outcomes compared with matched cohorts. Specifically, we evaluated 1) medical complications, 2) in-hospital lengths of stay (LOS), and 3) costs of care.

METHODS

Two cohorts of patients who underwent primary total hip arthroplasties from January 1, 2005 to March 31, 2014 were identified from the Medicare claims of the PearlDiver platform. Cohorts were matched by age, sex, and following comorbidities-anemia, diabetes, hyperlipidemia, hypertension, malnutrition, pulmonary disease, and renal failure, yielding 55,361 patients within the study (n = 9229) and matching cohorts (n = 46,132). Outcomes assessed included 90-day medical complications, in-hospital LOS, and costs of care. A P-value less than .005 was considered statistically significant.

RESULTS

Patients with Crohn's disease were found to have significantly higher incidences and odds ratios of 90-day medical complications (30.2 vs 13.8; odds ratios: 2.2, P < .0001). They were also found to have significantly longer LOS (3.8- vs 3.6-days, P < .0001) and higher day of surgery ($12,662.00 vs 12,271.15, P < .0001) and 90-day episode costs ($16,933.18 vs $15,670.32, P < .0001).

CONCLUSION

Crohn's disease is associated with higher rates of medical complications, longer in-hospital LOS, and increased costs of care. This study may aid physicians to perform appropriate risk adjustment for adverse outcomes and to educate these patients about potential postoperative complications in these patients.

摘要

背景

随着全球克罗恩病的发病率和患病率持续变化,北美地区的发病率一直在上升。本研究的目的是评估接受初次全髋关节置换术的克罗恩病患者的结局是否较匹配队列更差。具体而言,我们评估了 1)医疗并发症,2)住院时间(LOS)和 3)医疗费用。

方法

从 PearlDiver 平台的 Medicare 索赔中确定了 2005 年 1 月 1 日至 2014 年 3 月 31 日接受初次全髋关节置换术的两个队列的患者。通过年龄、性别和以下合并症(贫血、糖尿病、高脂血症、高血压、营养不良、肺部疾病和肾衰竭)对队列进行匹配,得出研究(n=9229)和匹配队列(n=46132)各有 55361 名患者。评估的结果包括 90 天医疗并发症、住院 LOS 和医疗费用。P 值小于 0.005 被认为具有统计学意义。

结果

患有克罗恩病的患者发现其 90 天医疗并发症的发生率和比值比显著更高(30.2%比 13.8%;比值比:2.2,P < 0.0001)。他们还发现住院时间明显延长(3.8-比 3.6-天,P < 0.0001),手术日费用(12662.00 美元比 12271.15 美元,P < 0.0001)和 90 天治疗费用(16933.18 美元比 15670.32 美元,P < 0.0001)也更高。

结论

克罗恩病与更高的医疗并发症发生率、更长的住院时间和更高的医疗费用相关。本研究可能有助于医生对不良结局进行适当的风险调整,并向这些患者告知潜在的术后并发症。

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