Department of Radiation Oncology, Cancer Institute of New Jersey, Rutgers University, New Brunswick, NJ, 08901, USA.
Department of Radiation Oncology, City of Hope National Medical Center, Duarte, CA, 91010, USA.
J Appl Clin Med Phys. 2021 Mar;22(3):273-278. doi: 10.1002/acm2.13184. Epub 2021 Feb 27.
To develop a method combining CT scout images with axial images to improve the localization accuracy of catheter tips in high-dose-rate (HDR) brachytherapy treatments.
CT scout images were utilized along with conventionally reconstructed axial images to aid the localization of catheter tips used during HDR treatment planning. A method was developed to take advantage of the finer image resolution of the scout images to more precisely identify the tip coordinates. The accuracies of this method were compared with the conventional method based on the axial CT images alone, for various slice thicknesses, in a computed tomography dose index (CTDI) head phantom. A clinical case which involved multiple interstitial catheters was also selected for the evaluation of this method. Locations of the catheter tips were reconstructed with the conventional CT-based method and this newly developed method, respectively. Location coordinates obtained via both methods were quantitatively compared.
Combination of the scout and axial CT images improved the accuracy of identification and reconstruction of catheter tips along the longitudinal direction (i.e., head-to-foot direction, more or less parallel to the catheter tracks), compared to relying on the axial CT images alone. The degree of improvement was dependent on CT slice thickness. For the clinical patient case, the coordinate differences of the reconstructed catheter tips were 2.6 mm ± 0.9 mm in the head-to-foot direction, 0.4 mm ± 0.2 mm in the left-to-right direction, and 0.6 mm ± 0.2 mm in the anterior-to-posterior direction, respectively.
Combining CT scout and axial images demonstrates the ability to provide a more accurate identification and reconstruction of the interstitial catheter tips for HDR brachytherapy treatment, especially in the longitudinal direction. The method developed in this work has the potential to be implemented clinically together with automatic segmentation in modern brachytherapy treatment planning systems, in order to improve the reconstruction accuracy of HDR catheters.
开发一种结合 CT 扫描图像和轴向图像的方法,以提高高剂量率(HDR)近距离治疗中导管尖端的定位精度。
利用 CT 扫描图像和常规重建的轴向图像来辅助 HDR 治疗计划中导管尖端的定位。开发了一种方法,利用扫描图像更精细的图像分辨率来更精确地确定尖端坐标。在 CT 剂量指数(CTDI)头部体模中,比较了不同层厚下该方法与仅基于轴向 CT 图像的常规方法的准确性。还选择了一个涉及多个间质导管的临床病例来评估该方法。分别使用常规 CT 基于方法和新开发的方法重建导管尖端的位置。定量比较两种方法获得的位置坐标。
与仅依赖轴向 CT 图像相比,扫描和轴向 CT 图像的组合可改善导管尖端在纵向方向(即头脚方向,或多或少与导管轨迹平行)的识别和重建的准确性。改进程度取决于 CT 层厚。对于临床患者病例,重建导管尖端的坐标差异在头脚方向为 2.6mm±0.9mm,左右方向为 0.4mm±0.2mm,前后方向为 0.6mm±0.2mm。
结合 CT 扫描和轴向图像,为 HDR 近距离治疗提供了一种更准确地识别和重建间质导管尖端的方法,特别是在纵向方向。本研究开发的方法有可能与现代近距离治疗计划系统中的自动分割一起在临床上实施,以提高 HDR 导管的重建精度。