ICAR-National Rice Research Institute, Cuttack, India.
National Agri-Food Biotechnology Institute, Mohali, India.
Physiol Plant. 2021 Apr;171(4):849-867. doi: 10.1111/ppl.13377.
Plants being sessile have evolved numerous mechanisms to meet the changing environmental and growth conditions. Plant pathogens are responsible for devastating disease epidemics in many species. Transporter proteins are an integral part of plant growth and development, and several studies have documented their role in pathogen disease resistance. In this review, we analyze the studies on genome-wide identifications of plant transporters like sugars will eventually be exported transporters (SWEET), multidrug and toxic compound extrusion (MATE) transporters, ATP-binding cassette (ABC) transporters, natural resistance-associated macrophage proteins (NRAMP), and sugar transport proteins (STPs), all having a significant role in plant disease resistance. The mechanism of action of these transporters, their solute specificity, and the potential application of recent molecular biology approaches deploying these transporters for the development of disease-resistant plants are also discussed. The applications of genome editing tools, such as CRIPSR/Cas9, are also presented. Altogether the information included in this article gives a better understanding of the role of transporter proteins during plant-pathogen interaction.
植物是固着生物，为了适应不断变化的环境和生长条件，进化出了许多机制。植物病原体是导致许多物种毁灭性疾病流行的罪魁祸首。转运蛋白是植物生长和发育的重要组成部分，已有多项研究记录了它们在病原体疾病抗性中的作用。在这篇综述中，我们分析了关于植物转运蛋白的全基因组鉴定研究，如糖最终会被运出的转运蛋白（SWEET）、多药和毒性化合物外排转运蛋白（MATE）、ATP 结合盒（ABC）转运蛋白、天然抗性相关巨噬细胞蛋白（NRAMP）和糖转运蛋白（STPs），它们在植物疾病抗性中都具有重要作用。还讨论了这些转运蛋白的作用机制、它们的溶质特异性，以及最近利用这些转运蛋白开发抗病植物的分子生物学方法的潜在应用。还介绍了基因组编辑工具，如 CRISPR/Cas9 的应用。总之，本文所包含的信息使人们更好地了解了转运蛋白在植物-病原体相互作用过程中的作用。
