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[天然及合成α-肾上腺素能拟似物质的药理学特性II]

[Pharmacological pecularities of natural and synthetic alpha-adrenomimetic substances II].

作者信息

Zonta F, Santagostino Barbone M G, Grana E

出版信息

Farmaco Sci. 1977 Nov;32(11):803-12.

PMID:336391
Abstract

The comparative examination of noradrenaline, octopamine, Privin and 2-phenylethylamine on the isolated rat vas deferens made under controlled conditions (1) has been extended by introducing more complex experimental conditions. Pretreatment of the animal with reserpine does not change the response to Privin, while the response to the maximal doses of noradrenaline is reduced; the response to octopamine remains unchanged while that of 2-phenyl-ethylamine is abolished.

摘要

在可控条件下(1)对去甲肾上腺素、章鱼胺、普里文和2-苯乙胺在离体大鼠输精管上进行的比较实验,通过引入更复杂的实验条件得到了扩展。用利血平对动物进行预处理不会改变对普里文的反应,而对最大剂量去甲肾上腺素的反应会降低;对章鱼胺的反应保持不变,而对2-苯乙胺的反应则消失。

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1
[Pharmacological pecularities of natural and synthetic alpha-adrenomimetic substances II].[天然及合成α-肾上腺素能拟似物质的药理学特性II]
Farmaco Sci. 1977 Nov;32(11):803-12.
2
[Pharmacologic peculiarities of natural and synthetic alpha-adrenomimetics].[天然和合成α-肾上腺素能激动剂的药理学特性]
Farmaco Sci. 1977 Oct;32(10):725-34.
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[Study of maximal response of the rat vas deferens. I - study of adrenergic amines with diverse mechanisms of action and the influence of cast concentration in the physiological solution].大鼠输精管最大反应的研究。I - 作用机制多样的肾上腺素能胺类及生理溶液中钙离子浓度影响的研究
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The serotonin paradox: drug-receptor interaction in rat vas deferens.血清素悖论:大鼠输精管中的药物-受体相互作用。
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Action of various sympathomimetic amines on the isolated stripped vas deferens of the guinea-pig.各种拟交感神经胺对豚鼠离体输精管的作用。
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Steric aspects of adrenergic drugs. II. Effects of DL isomers and desoxy derivatives on the reserpine-pretreated vas deferens.肾上腺素能药物的空间因素。II. DL异构体和脱氧衍生物对利血平预处理的输精管的影响。
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"Indirect" sympathomimetic effects of L(+)-isomers and desoxy derivatives.L(+)-异构体和脱氧衍生物的“间接”拟交感神经效应。
J Pharm Pharmacol. 1967 Mar;19(3):199-200. doi: 10.1111/j.2042-7158.1967.tb08069.x.
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[The effect of adrenotropic substances on contraction of the rat ductus deferens induced by the action of adrenaline and transmural stimulation].
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The effects of reserpine pretreatment on the D- and L-isomers of some sympathomimetic amines.
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