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[天然及合成α-肾上腺素能拟似物质的药理学特性II]

[Pharmacological pecularities of natural and synthetic alpha-adrenomimetic substances II].

作者信息

Zonta F, Santagostino Barbone M G, Grana E

出版信息

Farmaco Sci. 1977 Nov;32(11):803-12.

PMID:336391
Abstract

The comparative examination of noradrenaline, octopamine, Privin and 2-phenylethylamine on the isolated rat vas deferens made under controlled conditions (1) has been extended by introducing more complex experimental conditions. Pretreatment of the animal with reserpine does not change the response to Privin, while the response to the maximal doses of noradrenaline is reduced; the response to octopamine remains unchanged while that of 2-phenyl-ethylamine is abolished.

摘要

在可控条件下(1)对去甲肾上腺素、章鱼胺、普里文和2-苯乙胺在离体大鼠输精管上进行的比较实验,通过引入更复杂的实验条件得到了扩展。用利血平对动物进行预处理不会改变对普里文的反应,而对最大剂量去甲肾上腺素的反应会降低;对章鱼胺的反应保持不变,而对2-苯乙胺的反应则消失。

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