口腔癌中的转录组生物标志物：综合分析和癌症基因组图谱验证。
Transcriptional Biomarkers in Oral Cancer: An Integrative Analysis and the Cancer Genome Atlas Validation.
机构信息
The Gujarat Cancer & Research Institute, Civil Hospital Campus, Asarwa, Ahmedabad-380 016, Gujarat, India.
出版信息
Asian Pac J Cancer Prev. 2021 Feb 1;22(2):371-380. doi: 10.31557/APJCP.2021.22.2.371.
OBJECTIVE
An impervious mortality rate in oral cancer (OC) to a certain extent explains the exigencies of precise biomarkers. Therefore, the study was intended to identify OC candidate biomarkers using samples of healthy normal tissues (N=335), adjacent normal tissues (N=93) and OC tissues (N=533) from online microarray data.
METHODS
Differentially expressed genes (DEGs) were recognised through GeneSpring software (Fold change >4.0 and 'p' value.
目的
口腔癌（OC）的死亡率在一定程度上无法确定，这在某种程度上解释了精确生物标志物的必要性。因此，本研究旨在使用来自在线微阵列数据的健康正常组织（N=335）、相邻正常组织（N=93）和 OC 组织（N=533）样本，识别 OC 候选生物标志物。
方法
通过 GeneSpring 软件识别差异表达基因（DEGs）（倍数变化>4.0 和 'p' 值
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