Department of Pediatrics, Section of Rheumatology, Baylor College of Medicine, Houston, TX, USA; Texas Children's Hospital, Houston, TX, USA.
Departments of Pediatrics, Division of Infectious Diseases, and Community Health and Epidemiology, Canadian Center for Vaccinology, Dalhousie University, Halifax, NS, Canada.
Vaccine. 2021 May 21;39(22):3037-3049. doi: 10.1016/j.vaccine.2021.01.054. Epub 2021 Feb 25.
This is a Brighton Collaboration Case Definition of the term "Multisystem Inflammatory Syndrome in Children and Adults (MIS-C/A)" to be utilized in the evaluation of adverse events following immunization. The case definition was developed by topic experts convened by the Coalition for Epidemic Preparedness Innovations (CEPI) in the context of active development of vaccines for SARS-CoV-2. The format of the Brighton Collaboration was followed, including an exhaustive review of the literature, to develop a consensus definition and defined levels of certainty. The document underwent peer review by the Brighton Collaboration Network and by selected expert external reviewers prior to submission. The comments of the reviewers were taken into consideration and edits incorporated into this final manuscript.
这是用于评估疫苗接种后不良事件的“儿童和成人多系统炎症综合征（MIS-C/A）”术语的 Brighton 协作组病例定义。该病例定义是由流行病防范创新联盟（CEPI）召集的专题专家在积极开发 SARS-CoV-2 疫苗的背景下制定的。采用了 Brighton 协作组的格式，包括对文献进行详尽审查，以制定共识定义和确定确定性级别。该文件在提交前经过了 Brighton 协作网络和选定的专家外部审阅者的同行评审。审阅者的意见已被考虑在内，并在最终手稿中进行了编辑。
