Goldstein E J, Lewis R P, Martin W J, Edelstein P H
J Clin Microbiol. 1978 Oct;8(4):413-8. doi: 10.1128/jcm.8.4.413-418.1978.
A total of 64 isolates of Klebsiella ozaenae were recovered from 36 patients during a 40-month period. Over 7,500 isolates of K. pneumoniae were isolated during the same time period. Before this decade, K. ozaenae was considered to be only a colonizer of the nasopharynx or a putative cause of ozena (atrophic rhinitis). K. ozaenae was recovered most frequently from sputum in mixed culture but was associated with infection in 12 patients (2 with bacteremia, 3 with urinary tract infection, 1 with soft tissue infection, and 6 with mucopurulent nasal discharge). The spectrum of disease caused by this organism is more extensive than has been appreciated previously.
在40个月的时间里，从36名患者中总共分离出64株鼻硬结克雷伯菌。在同一时期分离出了超过7500株肺炎克雷伯菌。在这十年之前，鼻硬结克雷伯菌仅被认为是鼻咽部的定植菌或臭鼻症（萎缩性鼻炎）的假定病因。鼻硬结克雷伯菌最常从混合培养的痰液中分离出来，但与12名患者的感染有关（2例菌血症，3例尿路感染，1例软组织感染，6例黏液脓性鼻分泌物）。这种微生物引起的疾病谱比以前认识到的更为广泛。
