Department of Paediatrics, University of Perugia, Perugia, Italy.
Department of Paediatrics, University of L'Aquila, L'Aquila, Italy.
Acta Paediatr. 2021 Jun;110(6):1774-1777. doi: 10.1111/apa.15827. Epub 2021 Mar 21.
Children with COVID-19 tend to show milder symptoms than adults during the pandemic, but growing evidence of neurological involvement has emerged. Some studies have reported neurological symptoms in children with COVID-19, which include multisystem inflammatory syndrome, a disease that shares some, but not all, of the characteristics of Kawasaki disease. This review presents, and discusses, the evidence to date. Our initial findings suggest that neurological manifestations can be considered to be the direct result of central nervous system viral invasion or post-infection immuno-mediated disease.
儿童在大流行期间感染 COVID-19 的症状往往比成年人轻,但越来越多的神经受累证据已经出现。一些研究报告了 COVID-19 患儿的神经系统症状,包括多系统炎症综合征,这种疾病具有川崎病的一些特征,但并非全部。本综述介绍并讨论了迄今为止的证据。我们的初步发现表明,神经表现可被认为是中枢神经系统病毒入侵或感染后免疫介导疾病的直接结果。