HOS15-PWR chromatin remodeling complex positively regulates cold stress in .

Cold stress is a major environmental constraint that restrains plant growth and productivity. To cope with cold stress, plants must be able to perceive a cold signal and regulate the expression of cold-regulated () genes. In our recent study, we showed that HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE 15 (HOS15) acts as a substrate receptor for CULLIN4-based ubiquitin E3 ligase complex to promote cold-induced histone deacetylase 2 C (HD2C) degradation that allows the activation of genes. Additionally, we found that POWERDRESS (PWR), a HOS15-interacting protein, is required for the association of HOS15 with gene chromatin and HD2C degradation. The HOS15/PWR complex interacts with and recruits CBF transcription factors to the promoters of genes. Collectively, our previous findings suggest that HOS15 and PWR function as positive regulators for the expression of genes, and promote cold tolerance. Accordingly, we herein discuss the role of PWR in cold tolerance.