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通过设计进行预防:计算流体动力学建模的见解,以预测 3D 打印产生的超细颗粒暴露。

Prevention through design: insights from computational fluid dynamics modeling to predict exposure to ultrafine particles from 3D printing.

机构信息

NanoSafe, Inc., Blacksburg, VA, USA.

Chemistry & Industrial Hygiene, Inc., Wheat Ridge, CO, USA.

出版信息

J Toxicol Environ Health A. 2021 Jun 3;84(11):458-474. doi: 10.1080/15287394.2021.1886210. Epub 2021 Feb 28.

DOI:10.1080/15287394.2021.1886210
PMID:33641630
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8044021/
Abstract

Fused filament fabrication (FFF) 3D printers are increasingly used in industrial, academic, military, and residential sectors, yet their emissions and associated user exposure scenarios are not fully described. Characterization of potential user exposure and environmental releases requires robust investigation. During operation, common FFF 3D printers emit varying amounts of ultrafine particles (UFPs) depending upon feedstock material and operation procedures. Volatile organic compounds associated with these emissions exhibit distinct odors; however, the UFP portion is largely imperceptible by humans. This investigation presents straightforward computational modeling as well as experimental validation to provide actionable insights for the proactive design of lower exposure spaces where 3D printers may be used. Specifically, data suggest that forced clean airflows may create lower exposure spaces, and that computational modeling might be employed to predict these spaces with reasonable accuracy to assist with room design. The configuration and positioning of room air ventilation diffusers may be a key factor in identifying lower exposure spaces. A workflow of measuring emissions during a printing process in an ANSI/CAN/UL 2904 environmental chamber was used to provide data for computational fluid dynamics (CFD) modeling of a 6 m room. Measurements of the particle concentrations in a Class 1000 clean room of identical geometry were found to pass the Hanna test for agreement between model and experimental data, validating the findings.

摘要

熔融沉积成型(FFF)3D 打印机越来越多地应用于工业、学术、军事和住宅等领域,但其排放物及其相关的用户暴露情况尚未完全描述。要对潜在的用户暴露和环境排放进行特征描述,需要进行强有力的调查。在运行过程中,常见的 FFF 3D 打印机根据原料材料和操作程序,会排放出不同数量的超细颗粒(UFPs)。与这些排放物相关的挥发性有机化合物具有明显的气味;然而,人类对 UFP 部分的感知能力很低。本研究通过简单的计算建模和实验验证,为主动设计 3D 打印机可能使用的低暴露空间提供了可行的见解。具体而言,数据表明强制清洁气流可能会创造低暴露空间,并且可以使用计算建模来合理准确地预测这些空间,以协助房间设计。房间空气通风扩散器的配置和位置可能是确定低暴露空间的一个关键因素。在 ANSI/CAN/UL 2904 环境室中进行打印过程排放测量的工作流程,为 6 米房间的计算流体动力学(CFD)建模提供了数据。在相同几何形状的 1000 级洁净室中对颗粒浓度进行的测量,通过模型与实验数据之间的一致性 Hanna 测试,验证了研究结果。

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Characteristics of nanoparticle formation and hazardous air pollutants emitted by 3D printer operations: from emission to inhalation.3D打印机操作中纳米颗粒形成及有害空气污染物的特征:从排放到吸入
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Human exposure to metals in consumer-focused fused filament fabrication (FFF)/ 3D printing processes.消费者导向的熔融沉积成型(FFF)/3D 打印过程中人类接触金属的情况。
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职业环境中使用3D打印机产生的排放物与健康风险。
J Toxicol Environ Health A. 2020 Apr 2;83(7):279-287. doi: 10.1080/15287394.2020.1751758. Epub 2020 Apr 21.
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Exposure to ambient fine particulate matter is associated with changes in fasting glucose and lipid profiles: a nationwide cohort study.暴露于环境细颗粒物与空腹血糖和血脂谱的变化有关:一项全国性队列研究。
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