Division of Cardiology, Department of Internal Medicine, St. Marianna University School of Medicine, Japan.
Syncope Unit, Toyoko Hospital, St. Marianna University School of Medicine, Japan.
Intern Med. 2021 Aug 15;60(16):2633-2637. doi: 10.2169/internalmedicine.6635-20. Epub 2021 Mar 1.
We herein report the case of a 20-year-old man with a history of epilepsy who presented with frequent transient loss of consciousness (T-LOC) and polymorphic ventricular tachycardia (VT) with QT interval prolongation. Blood investigations revealed panhypopituitarism. Following a biopsy, he was diagnosed with brain germinoma. During the biopsy, he had an episode of polymorphous VT with QT prolongation. There was no recurrence of T-LOC following chemotherapy and hormone replacement therapy. This case indicates the importance of checking the QT interval in patients with T-LOC, including those with seizures and brain tumors, to ensure appropriate treatment.
我们在此报告一例 20 岁男性癫痫病史，频繁出现短暂性意识丧失（T-LOC）和多形性室性心动过速（VT）伴 QT 间期延长。血液检查发现垂体功能减退症。活检后，他被诊断为脑生殖细胞瘤。在活检过程中，他出现了 QT 延长的多形性 VT 发作。化疗和激素替代治疗后，T-LOC 无复发。本例表明，对于 T-LOC 患者，包括癫痫和脑肿瘤患者，检查 QT 间期非常重要，以确保进行适当的治疗。
