Iraninezhad Zakaria, Azizzadeh Mohammad, Taghavi Razavizadeh Alireza, Mehrzad Jalil, Rashtibaf Mohammad
Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
Vet Res Forum. 2020 Fall;11(4):423-426. doi: 10.30466/vrf.2019.101946.2429. Epub 2020 Dec 15.
is a Gram-negative intracellular bacteria responsible for major economic losses due mainly to infection and subsequent induction of abortion in several animal species and poses considerable public health problems in humans. This study was conducted to determine the prevalence of antibody against in sheep and goat population of Khorasan Razavi province located in northeastern Iran. Four hundred fifty-two (271 sheep and 181 goats) sera samples from 40 sheep/goat epidemiologic units located in 11 counties were selected. Sera were assayed for antibodies against using ELISA assay. Out of 452 sheep and goat sera, 44 [9.70% (95.00%CI: 7.10%-12.40%)] were positive for antibodies. 28 out of 40 epidemiologic units (70.00%) and 10 out of 11 counties (91.00%), at least one seropositive sample was found. There was no significant difference between the seropositivity of sheep and goats. Age, sex, and location did not show significant relationship with the test results. The results showed that was circulating in wide parts of Khorasan Razavi province. Considering the economic and public health importance of , measures should be taken to help prevent its spread and to reduce the zoonotic risk of in the studied region.
是一种革兰氏阴性胞内菌,主要由于感染以及随后在多种动物物种中引发流产而导致重大经济损失,并且给人类带来相当大的公共卫生问题。本研究旨在确定位于伊朗东北部的呼罗珊拉扎维省绵羊和山羊群体中针对该菌抗体的流行情况。从位于11个县的40个绵羊/山羊流行病学单位选取了452份(271份绵羊血清和181份山羊血清)血清样本。使用酶联免疫吸附测定法检测血清中针对该菌的抗体。在452份绵羊和山羊血清中,44份[9.70%(95.00%置信区间:7.10%-12.40%)]该菌抗体呈阳性。在40个流行病学单位中的28个(70.00%)以及11个县中的10个(91.00%)发现了至少一份血清阳性样本。绵羊和山羊的血清阳性率之间没有显著差异。年龄、性别和地理位置与检测结果均未显示出显著关系。结果表明该菌在呼罗珊拉扎维省的广泛地区传播。鉴于该菌在经济和公共卫生方面的重要性,应采取措施帮助预防其传播并降低该菌在研究区域的人畜共患病风险。