Bazzout Asmae, Lachkar Azzeddine, Benfadil Drissia, Tsen Adil Abdenbi, El Ayoubi Fahd, Ghailan Rachid
University Hospital Center Mohamed VI Oujda, Morocco.
Faculty of Medicine and Pharmacy Oujda, Morocco.
Ann Med Surg (Lond). 2021 Feb 10;63:102166. doi: 10.1016/j.amsu.2021.02.012. eCollection 2021 Mar.
and importance: this case report aimed at an unusual case of extensive rhinoscleroma with a literature review, We report this case to bring attention to the patients with immunodeficiency problem regardless of presenting symptoms. Case presentation: a 70 -year-old patient with diabetes and hypertension, consulted for chronic median and posterior headaches have not improved with symptomatic treatment. She reported cacosmia without rhinorrhea and right otalgia. The examination of the nasal cavity showed a bleeding lesion on the lateral wall of the nasopharynx. CT-scan of the facial showed tissue lesion on the posterior and lateral walls of the nasopharynx, with infiltration of the parapharyngeal space and bone lysis right edge of the clivus. The biopsy confirmed the diagnosis of rhinoscleroma. The patient started the ciprofloxacin for 3 months, and the evolvement has noticed with the disappearance of the lesion during the first month of treatment. The patient started the ciprofloxacin for 3 months, and the evolvement was noticed with the disappearance of the lesion during the first month of treatment. Cilinical discussion: rhinoscleroma is a chronic and progressive granulomatous disease of the nasal cavities. The diagnosis is confirmed by the search for bacteria and an anatomopathological assessment of MIKULICZ cells. The medical treatment of choice has a high concentration in macrophages such as rifampicin and fluoroquinolone. Conclusion: rhinoscleroma is a granulomatous disease caused by klebsiella rhinoscleromatis, you must think about in front a nasopharyngeal lesion imitating a malignant pathology.
本病例报告旨在介绍一例罕见的广泛性鼻硬结病,并进行文献综述。我们报告此病例是为了引起对免疫缺陷问题患者的关注,无论其呈现何种症状。病例介绍:一名70岁患有糖尿病和高血压的患者,因慢性中后头痛前来咨询,对症治疗后未见改善。她报告有嗅觉障碍但无鼻漏及右耳痛。鼻腔检查显示鼻咽侧壁有一出血性病变。面部CT扫描显示鼻咽后壁和侧壁有组织病变,咽旁间隙有浸润,斜坡右缘有骨质溶解。活检确诊为鼻硬结病。患者开始服用环丙沙星3个月,在治疗的第一个月病变消失,病情出现好转。临床讨论:鼻硬结病是鼻腔的一种慢性进行性肉芽肿性疾病。通过查找细菌和对米库利奇细胞进行解剖病理学评估来确诊。首选的药物治疗是在巨噬细胞中有高浓度的药物,如利福平和氟喹诺酮。结论:鼻硬结病是由鼻硬结克雷伯菌引起的肉芽肿性疾病,面对疑似恶性病变的鼻咽部病变时必须考虑到该病。